MOF sensors for food safety: ultralow detection of putrescine and cadaverine in protein rich foods

Leelasree, T.; Aggarwal, Himanshu

doi:10.1039/d1tc05422h

Cited by 30 publications

(20 citation statements)

References 35 publications

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“…Two cobalt-based metal–organic frameworks (MOFs) were developed for polyamine detection, wherein a strong emission at about 332 nm was largely quenched by spermine, spermidine, or putrescine [ 69 ]. Since host–guest interactions between the polyamines and the MOFs were involved, the donor-acceptor electron transfer process from polyamines to MOFs generated photoinduced electron transfer (PET), leading to fluorescence quenching.…”

Section: Polyamine Detection Methodsmentioning

confidence: 99%

Recent Advances in Fluorescent Methods for Polyamine Detection and the Polyamine Suppressing Strategy in Tumor Treatment

Wang

Ran

et al. 2022

Biosensors

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The biogenic aliphatic polyamines (spermine, spermidine, and putrescine) are responsible for numerous cell functions, including cell proliferation, the stabilization of nucleic acid conformations, cell division, homeostasis, gene expression, and protein synthesis in living organisms. The change of polyamine concentrations in the urine or blood is usually related to the presence of malignant tumors and is regarded as a biomarker for the early diagnosis of cancer. Therefore, the detection of polyamine levels in physiological fluids can provide valuable information in terms of cancer diagnosis and in monitoring therapeutic effects. In this review, we summarize the recent advances in fluorescent methods for polyamine detection (supramolecular fluorescent sensing systems, fluorescent probes based on the chromophore reaction, fluorescent small molecules, and fluorescent nanoparticles). In addition, tumor polyamine-suppressing strategies (such as polyamine conjugate, polyamine analogs, combinations that target multiple components, spermine-responsive supramolecular chemotherapy, a combination of polyamine consumption and photodynamic therapy, etc.) are highlighted. We hope that this review promotes the development of more efficient polyamine detection methods and provides a comprehensive understanding of polyamine-based tumor suppressor strategies.

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Section: Polyamine Detection Methodsmentioning

confidence: 99%

Recent Advances in Fluorescent Methods for Polyamine Detection and the Polyamine Suppressing Strategy in Tumor Treatment

Wang

Ran

et al. 2022

Biosensors

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“…25−27 Recently, our group has also investigated MOFs for fluorescence and electrochemical sensing applications. 28,29 Encouraged by our recent findings, we have designed the first MOF-based dual sensor for nicotine detection. Such dual sensors can be highly useful in the preparation of nanocomposites for real-time sensing applications.…”

Section: ■ Introductionmentioning

confidence: 99%

“…30−32 Here, we report nicotine detection using two Co-based MOFs, BITSH-1 and BITSH-2 (Birla Institute of Technology and Science, Hyderabad). Both the MOFs were synthesized solvothermally as per our recent report 29 (Figure 1). BITSH-1 and BITSH-2 crystallize in the monoclinic P2 1 /n and orthorhombic Pbcn space groups, respectively.…”

Section: ■ Introductionmentioning

confidence: 99%

“…Metal–organic frameworks (MOFs), inorganic–organic hybrid porous materials with tuneable properties, have been explored for various applications. , These can also be promising candidates as fluorescent and electrochemical sensors due to the feasibility of placing fluorescent linkers and metal/ligand redox centers inside the framework. MOFs have been explored for sensing of diverse analytes, − but there is only a handful of reports on nicotine detection using MOFs. − Recently, our group has also investigated MOFs for fluorescence and electrochemical sensing applications. , Encouraged by our recent findings, we have designed the first MOF-based dual sensor for nicotine detection. Such dual sensors can be highly useful in the preparation of nanocomposites for real-time sensing applications.…”

Section: Introductionmentioning

confidence: 99%

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MOF-Based Dual Sensor for the Electrochemical and Fluorescence Detection of Nicotine

Leelasree

Goel

Aggarwal

2022

ACS Appl. Nano Mater.

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Detection of nicotine is highly desired; therefore, there is an endless need to develop multifunctional sensors that can detect nicotine in more than one way. Metal−organic frameworks, a class of porous hybrid materials known for their tunability, can be strong candidates for developing nicotine sensors. In this work, we have developed a pure Metal−organic framework (MOF)based dual sensor for the highly selective detection of nicotine. Interestingly, the sensor can efficiently detect nicotine using fluorescence and electrochemical sensing technique with a detection limit as low as 0.25 μM. Real cigarette and urine samples have been studied to evaluate the nicotine content in actual conditions where the sensor shows nearly 100% nicotine recovery. Selectivity experiments demonstrate that the MOF sensor can efficiently detect nicotine in the presence of other interfering analytes such as glucose, dopamine, and various metal salts. A plausible mechanism has been described for the MOFs' nicotine-sensing ability and Xray photoelectron spectroscopy (XPS) analysis shows that nicotine is present in the MOF samples after the sensing experiment.

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“…7 MOFs have been exploited for various applications such as sensing, storage, separation, etc. 8–10 MOFs’ structure tunability offers a unique advantage of putting either redox-active metals or ligands or both in the same framework. This makes MOFs strong candidates for designing multichromic materials.…”

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confidence: 99%

Electrochromic and photochromic behaviour in a single metal–organic framework containing a redox-active linker

et al. 2022

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MOF sensors for food safety: ultralow detection of putrescine and cadaverine in protein rich foods

Abstract: Two Co-based fluorescent MOFs are reported to detect biogenic amines in protein rich foods like fish and cheese.

Cited by 30 publications

References 35 publications

Recent Advances in Fluorescent Methods for Polyamine Detection and the Polyamine Suppressing Strategy in Tumor Treatment

Recent Advances in Fluorescent Methods for Polyamine Detection and the Polyamine Suppressing Strategy in Tumor Treatment

MOF-Based Dual Sensor for the Electrochemical and Fluorescence Detection of Nicotine

Electrochromic and photochromic behaviour in a single metal–organic framework containing a redox-active linker

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