Möglichkeiten und Perspektiven der Hyperspektralbildgebung in der Viszeralchirurgie

Gockel, Ines; Jansen-Winkeln, Boris; Holfert, N; Rayes, Nada; Thieme, René; Maktabi, Marianne; Sucher, Robert; Seehofer, Daniel; Barberio, Manuel; Diana, Michèle; Rabe, SM; Mehdorn, Matthias; Moulla, Yusef; Niebisch, Stefan; Branzan, Daniela; Rehmet, K.; Takoh, JP; Petersen, Tim-Ole; Neumuth, Thomas; Melzer, Andreas; Chalopin, Claire; Köhler, Helmut

doi:10.1007/s00104-019-01016-6

Cited by 21 publications

(23 citation statements)

References 21 publications

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“…In this clinical trial, both imaging methods proved to be feasible, simple, and reliable with minimal differences according to measurement inaccuracies. While HSI is known as a noninvasive and contactless imaging method [18], the literature describes a small percentage of allergic complications caused by ICG administration [31]. In our current study, there were no complications due to the injected agent and the procedure of FA turned out to be safe.…”

Section: Discussionsupporting

confidence: 52%

“…Hyperspectral imaging (HSI) is a relatively new established intraoperative imaging method, which enables the objective measurement of physiological tissue parameters. Measurements are characterized by their noninvasiveness and their freedom of contact and contrast agents [18]. HSI has already been applied in a wide medical spectrum, including the assessment of tissue perfusion, tissue classification, wound healing, or the detection of cancer [19].…”

Section: Introductionmentioning

confidence: 99%

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Comparison of hyperspectral imaging and fluorescence angiography for the determination of the transection margin in colorectal resections—a comparative study

Jansen-Winkeln

Germann

Köhler

et al. 2020

Int J Colorectal Dis

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Purpose One relevant aspect for anastomotic leakage in colorectal surgery is blood perfusion of both ends of the anastomosis. The clinical evaluation of this issue is limited, but new methods like fluorescence angiography with indocyanine green or non-invasive and contactless hyperspectral imaging have evolved as objective parameters for perfusion evaluation. Methods In this prospective, non-randomized, open-label and two-arm study, fluorescence angiography and hyperspectral imaging were compared in 32 consecutive patients with each other and with the clinical assessment by the surgeon. After preparation of the bowel and determination of the surgical resection line, the tissue was evaluated with hyperspectral imaging for 5 min before and after cutting the marginal artery and assessed by 6 hyperspectral pictures followed by fluorescence angiography with indocyanine green. Results In 30 of 32 patients, the image data could be evaluated and compared. Both methods provided a comparable borderline between well-perfused and poorly perfused tissue (p = 0.704). In 15 cases, the surgical resection line was shifted to the central position due to the imaging. The border zone was sharper in fluorescence angiography and best assessed 31 s after injection. With hyperspectral imaging, the border zone was visualized wider and with more differences between proximal and distal border. Conclusion Hyperspectral imaging and fluorescence angiography provide similar results in determining the perfusion border. Both methods allow a good and safe visualization of the blood perfusion at the central resection margin to create a well-perfused anastomosis. Trial registration This study was registered at Clinicaltrials.gov (NCT04226781) on January 13, 2020.

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Section: Discussionsupporting

confidence: 52%

Section: Introductionmentioning

confidence: 99%

Comparison of hyperspectral imaging and fluorescence angiography for the determination of the transection margin in colorectal resections—a comparative study

Jansen-Winkeln

Germann

Köhler

et al. 2020

Int J Colorectal Dis

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“…Die HSI-Parameter Perfusion, Oxygenierung, Hämoglobin-Index und Gewebe-Wassergehalt intraabdomineller Organe/Strukturen sowie deren Aussagekraft für die Abdominalchirurgie sind zusammengefasst in ▶ Tab. 1 dargestellt (nach [5]).…”

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“…Aus den analysierten Lichtspektren können Indexparameter, wie in ▶ Tab. 1 zusammengefasst, berechnet werden (nach [5]), deren Werte in Bildintensitäten zur Visualisierung codiert werden. Somit können Informationen, die normalerweise für das menschliche Auge unsichtbar sind, sichtbar gemacht werden.…”

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