Moist Toilet Paper: Allergy to the Nonhalogenated Derivative Methylisothiazolinone Preservative Alone

Contact allergy to methylisothiazolinone in a deodorant

“…Six of them suffered from perineal eczema caused by wipes, and one from eyelid dermatitis resulting from make‐up removal. Since then, other cases have been reported (7). In a retrospective investigation performed by Lundov et al, in which 2536 dermatitis patients were patch tested with MI (4), exposure caused by cosmetics, namely in hair care products, liquid soaps, creams, cleansing milk, and a suntan lotion, was found in 32% of the cases.…”

Outbreak of contact sensitization to methylisothiazolinone: an analysis of French data from the REVIDAL‐GERDA network

“…Additionally, it has been increasingly used in leave‐on products, such as wet wipes for various purposes (intimate hygiene or domestic use) and cosmetics. Baby and intimate wipes are applied under occlusion, increasing penetration of the allergen . Since the introduction of this preservative, the emergence of allergic contact dermatitis has been reported .…”