Introduction: Difference in design of distalization appliances resulted in a difference in dimensions of dental arch after ending of distalization. Objectives: The current study aimed to evaluate transverse dental changes caused by using both 2K-loop and pendulum appliances, and to compare different effects of both appliances using transverse dental measurements. Material and methods: Study group included 16 participants with dental bilateral full cusp or end-to-end class II molar relationship equally divided into two groups. First group, 2K-loop group, consisted of 5 girls and 3 boys (mean age, 10.8 ± 1.2 years) treated with PB applied 2K-loop appliance. Second group, pendulum group included 5 girls and 3 boys (mean age, 11.1 ± 1.1 years) treated with palatally applied pendulum appliance. Study models were taken at the beginning of treatment and at the end of molar distalization. Paired samples t-test was applied to evaluate mean changes during treatment in each group, and to compare measurement differences between the two groups. Results: Statistical analysis of the measurements showed an increase in inter-molar distance of the first molars in the two groups. The increase was significant in the 2K-loop group, with 4.33 ± 0.81 mm, and not significant in the pendulum group (2.19 ± 2.00 mm). There was a significant distal rotation in the upper right first molars of 7.83° ± 2.92°, and 8.66° ± 2.73° on the left with PB 2K-loop appliance. Also, significant mesial rotation on the upper right first molars was observed with 4.83° ± 3.97°, and 4.83° ± 2.71° on the left with palatally applied pendulum appliance. Conclusions: PB acting on 2K-loop appliance causes an increase in the inter-molar distance and distal rotation of maxillary first molars. Palatally acting pendulum appliance results in mesial rotation of maxillary first molars. In cases where maxillary molars need to be de-rotated and to increase inter-molar distance, PB 2K-loop appliance is a better choice.