Molecular biology of head and neck cancer

Gudiseva, Swetha; Katappagari, Kiran K; Kantheti, Lalith Prakash Chandra; Poosarla, Chandrashekar; Gontu, Sridhar Reddy; Baddam, Venkat Ramana Reddy

doi:10.4103/2277-8632.202584

J NTR Univ Health Sci

2017

DOI: 10.4103/2277-8632.202584

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Molecular biology of head and neck cancer

Swetha Gudiseva

Kiran K Katappagari

Lalith Prakash Chandra Kantheti

et al.

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Molecular Pathogenesis of Oral Squamous Cell Carcinoma

Jain¹

2020

Squamous Cell Carcinoma - Hallmark and Treatment Modalities

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Oral carcinogenesis is a molecular and histological multistage process featuring genetic and phenotypic molecular markers which involves enhanced function of several protooncogenes, oncogenes and/or the deactivation of tumor suppressor genes, resulting in the over activity of growth factors and its cell surface receptors, which could enhance messenger signaling intracellularly, and/or leads to the increased production of transcription factors. Alone oncogenes are not responsible for carcinogenesis, genes having tumor suppressor activity, leads to a phenotypic change in cell which is responsible for increased cell proliferation, loss of cellular cohesion, and the ability to infiltrate local tissue and spread to distant sites. Understanding the molecular interplay of both onco and tumor genes will allow more accurate diagnosis and assessment of prognosis, which might lead the way for novel approaches to treatment.

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Molecular Pathogenesis of Oral Squamous Cell Carcinoma

Jain¹

2020

Squamous Cell Carcinoma - Hallmark and Treatment Modalities

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Molecular biology of head and neck cancer

Cited by 1 publication

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Molecular Pathogenesis of Oral Squamous Cell Carcinoma

Molecular Pathogenesis of Oral Squamous Cell Carcinoma

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