Molecular characterization of a Toll-like receptor 22 homologue in large yellow croaker (Pseudosciaena crocea) and promoter activity analysis of its 5′-flanking sequence

Xiao, Xiaoqiang; Qin, Qi; Chen, Xinhua

doi:10.1016/j.fsi.2010.10.014

Cited by 60 publications

(38 citation statements)

References 34 publications

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“…exon. A similar result was found for DrTLR22 [29] and OmTLR22 [14], but it was different for TrTLR22 [16], PoTLR22 [12], and LcTLR22 [17], which had four, three and three introns, respectively (Fig. 4).…”

Section: Discussionsupporting

confidence: 81%

“…The domain structure of CiTLR22 was similar to CcTLR22 (C. carpio, ADR66025.1), DrTLR22 (D. rerio, AAI63527.1) and CaTLR (C. auratus, AAO19474.1), but the number of LRR varies slightly between different fish species. There are 18, 17, 15, 15, 20, 15 and 16 LRRs in LcTLR22 [17], OmTLR22 [14], TrTLR22 [16], CaTLR22 [15], PoTLR22 [12], DrTLR22 [29] and CcTLR22 [30], respectively. The LRR domain of TLR has been implicated in ligand binding [31,32], and it is an open question whether the variation in the LRR domain changes the ligand affinity of fish TLR22.…”

Section: Discussionmentioning

confidence: 99%

“…This result was partially consistent with gene expression patterns in other teleost fish species. In puffer fish, rainbow trout, Japanese flounder and large yellow crocker, the TLR22 gene was most prominently expressed in one or both of these tissues [8,12,14,17]. In contrast, the TLR3 gene was mainly expressed in liver, intestine, and trunk kidney in common carp [35], and in catfish the highest expression level was in liver and muscle [41].…”

Section: Discussionmentioning

confidence: 99%

“…In rainbow trout, formalin-inactivated A. salmonicida pathogens induce TLR22 expression up to eight-fold in vitro in peripheral blood lymphocytes and in tissues from spleen and head kidney [14]. In large yellow croaker, upon stimulation with poly (I:C), the TLR22 expression was obviously upregulated in head kidney and spleen tissues, and also in primary head kidney cells [17].…”

Section: Introductionmentioning

confidence: 99%

“…Subsequently, it was identified in fugu (Takifugu rubripes) [16], Japanese flounder (Paralichthys olivaceus) [12], rainbow trout (Oncorhynchus mykiss) [14], zebrafish (Danio rerio) [9] and large yellow croaker (Pseudosciaena crocea) [17]. It was postulated that these TLRs were lost in the mammalian lineage ever since the separation from the fish lineage, approximately 400 million years ago [18].…”

Section: Introductionmentioning

confidence: 99%

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Cloning and characterization of the grass carp (Ctenopharyngodon idella) Toll-like receptor 22 gene, a fish-specific gene

Huang

et al. 2012

Fish & Shellfish Immunology

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Section: Discussionsupporting

confidence: 81%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Cloning and characterization of the grass carp (Ctenopharyngodon idella) Toll-like receptor 22 gene, a fish-specific gene

Huang

et al. 2012

Fish & Shellfish Immunology

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Innate Immunity

Dalmo

Bøgwald

2022

Principles of Fish Immunology

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Research on the innate immunity has accelerated over the last decades. The main reason for this has been the discovery of receptors recognizing danger molecules from pathogens. This has been facilitated through genome and transcriptome sequencing of different fish species. Also, endogenous host molecules from sterile physiological insults may also bind to certain receptors and induce immunological processes. The magnitude and quality of adaptive immunity are known to be dependent on the instructions the innate response gives. This chapter gives an overview of selected innate immune organs/tissues, factors, and processes that have been suggested to possess important roles during innate immune response in fish.

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Comprehensive survey and genomic characterization of Toll-like receptors (TLRs) in channel catfish, Ictalurus punctatus: identification of novel fish TLRs

Quiniou¹,

Boudinot²,

Bengtén³

2013

Immunogenetics

123

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A comprehensive survey of channel catfish Toll-like receptors (TLRs) was undertaken following a genomic PCR approach based on degenerate primers. Twenty different TLRs were identified in channel catfish. Channel catfish TLR sequences were characterized by phylogenetic analysis based on their conserved Toll/interleukin-1 receptor domain and by in-depth analysis of leucine-rich repeat (LRR) motifs of the ligand binding extracellular domain (ECD). The catfish have representatives of all the TLR types defined in vertebrates with the exception of TLR6, TLR10, TLR11, TLR12, TLR13, TLR15, TLR23, and TLR24. Additionally, two new types were discovered: TLR25 and TLR26. TLR25 is also present in cyprinids, cichlids, plecoglossids, and adrianichthyids, suggesting its presence early in fish evolution. To date, TLR26 was found only in channel catfish. Like TLR18-23, TLR25 and TLR26 were not found in any other vertebrate classes and appear to be fish specific. Data mining using the catfish TLR sequences revealed that in addition to ictalurids and cyprinids, TLR4 is also present in salmonids. TLR19 and TLR20 were both found in ictalurids, cyprinids, and salmonids, demonstrating a wider range than previously known. The LRR structure within ECDs appeared generally well conserved. TLR7 demonstrated a very high identity to human TLR7 strongly suggesting that ligand specificity maybe conserved. Finally, expression profiling confirmed that most TLRs are widely expressed in a diversity of tissues and revealed marked differences of expression level.

show abstract

Molecular characterization of a Toll-like receptor 22 homologue in large yellow croaker (Pseudosciaena crocea) and promoter activity analysis of its 5′-flanking sequence

Cited by 60 publications

References 34 publications

Cloning and characterization of the grass carp (Ctenopharyngodon idella) Toll-like receptor 22 gene, a fish-specific gene

Cloning and characterization of the grass carp (Ctenopharyngodon idella) Toll-like receptor 22 gene, a fish-specific gene

Innate Immunity

Comprehensive survey and genomic characterization of Toll-like receptors (TLRs) in channel catfish, Ictalurus punctatus: identification of novel fish TLRs

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