Molecular characterization of chicken infectious anaemia virus (CIAV) in China during 2020–2021

Sun, Hejing; Yu, Shuxun; Jiang, Tianhua; Zhang, Yan; Wang, Dingai; Chen, Li; Zhou, Qingfeng; Yin, Lei; Chen, Feng

doi:10.1080/03079457.2022.2155109

Cited by 2 publications

(1 citation statement)

References 61 publications

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“…This result suggests that CIAVs currently persist and circulate in the chicken population across Vietnam with high prevalence. Prevalence of CIAVs in Vietnam was relatively equivalent to that of other Asian neighboring countries, namely China, Thailand, and Malaysia, which ranged from around 40% to 70% ( Hailemariam et al ., 2008 ; Chansiripornchai, 2016 ; Sun et al ., 2022 ). It is noteworthy that we selected to collect samples from chickens with suspected CIAV infection signs such as anorexia, weakness, petechiation, and ecchymoses, lethargy.…”

Section: Discussionmentioning

confidence: 99%

First detection and genetic characterization of chicken infectious anemia virus in the Mekong Delta, Vietnam

Hiển¹,

Tran²,

Bích³

et al. 2023

Open Vet J

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Background: Chicken infectious anemia (CIA) caused by chicken infectious anemia virus (CIAV) is considered one of the most important immunosuppressive diseases affecting chicken and recently poses a great economic burden to the poultry industry worldwide. Aim: This study aims to identify the presence of CIAV in the Mekong delta (MD), Vietnam and to determine genotypes of CIAVs that are currently circulating in this area. Methods: Organ samples (spleen, liver, and thymus) of 144 chickens suspected with CIA from 47 poultry farms were collected. A total of 47 pooled samples, each containing two to four chickens of each farm, were tested for the presence of CIAV. Results: Twenty out of 47 pooled organ samples (pool of two to four chickens per farm) were positive for CIAV using PCR targeting the viral VP1 gene. The VP1 amplicons of eight representative CIAVs were subjected for sequencing and genetic characterization. Phylogenetic analysis based on partial VP1 gene sequence revealed that the CIAVs detected in the MD grouped into different genotypes of II, IIIa, and IIIc together with CIAVs previously detected in the northern Vietnam and other Asian countries. The phylogenetic analysis also confirmed that detected CIAVs genetically differed from vaccine strains. In addition, deduced amino acids of the VP1 identified several critical amino acid substitutions in the VP1 protein that are likely associated with the virulence of CIAV. Conclusion: This is the first report to detect and determine genetic characterization of the circulating CIAVs in the MD. Therefore, this study provides important understanding on the evolution of CIAVs and highlights the importance of implementing prompt control measures against CIAVs in the MD and Vietnam.

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Section: Discussionmentioning

confidence: 99%

First detection and genetic characterization of chicken infectious anemia virus in the Mekong Delta, Vietnam

Hiển¹,

Tran²,

Bích³

et al. 2023

Open Vet J

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Gyrovirus: current status and challenge

Yan,

Wang,

et al. 2024

Front. Microbiol.

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Gyrovirus (GyV) is small, single-stranded circular DNA viruses that has recently been assigned to the family Anelloviridae. In the last decade, many GyVs that have an apparent pan-tropism at the host level were identified by high-throughput sequencing (HTS) technology. As of now, they have achieved global distribution. Several species of GyVs have been demonstrated to be pathogenic to poultry, particularly chicken anemia virus (CAV), causing significant economic losses to the global poultry industry. Although GyVs are highly prevalent in various birds worldwide, their direct involvement in the etiology of specific diseases and the reasons for their ubiquity and host diversity are not fully understood. This review summarizes current knowledge about GyVs, with a major emphasis on their morphofunctional properties, epidemiological characteristics, genetic evolution, pathogenicity, and immunopathogenesis. Additionally, the association between GyVs and various diseases, as well as its potential impact on the poultry industry, have been discussed. Future prevention and control strategies have also been explored. These insights underscore the importance of conducting research to establish a virus culture system, optimize surveillance, and develop vaccines for GyVs.

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Molecular characterization of chicken infectious anaemia virus (CIAV) in China during 2020–2021

Cited by 2 publications

References 61 publications

First detection and genetic characterization of chicken infectious anemia virus in the Mekong Delta, Vietnam

First detection and genetic characterization of chicken infectious anemia virus in the Mekong Delta, Vietnam

Gyrovirus: current status and challenge

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