Molecular characterization of fungal endophyte diversity isolated from Aconitum heterophyllum: a critically endangered medicinal plant of Kashmir Himalaya

Hafeez, Sabira; Yaqoob, Sabba; Magray, Aqib Rehman; Kamili, Azra N.; Ganai, Bashir Ahmad

doi:10.1007/s10123-023-00331-7

Cited by 5 publications

(3 citation statements)

References 64 publications

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“…Bjerkandera sp. endophytic strain was reported by Hafeez et al [32] from a medicinal plant of Kashmir Himalaya. In another study conducted in Hainan province of China, Phellinus sp.…”

Section: Discussionmentioning

confidence: 99%

Evaluating the Biocontrol Efficacy and Antioxidant Potential of Phellinus caribaeo‐quercicola—A First Report Dual‐Action Endophyte From Inula racemosa Hook. F.

Majid,

Wani,

Ganai

2024

J Basic Microbiol

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Phellinus caribaeo‐quercicola is a basidiomycetous fungus, isolated as an endophyte in this study from the healthy and symptomless leaves of Inula racemosa Hook. f., an important medicinal herb growing in Kashmir Himalaya. This study combines morphological, molecular and phylogenetic techniques to identify the fungal endophyte, using the ITS sequence of nrDNA. A detached leaf assay was conducted to assess the pathogenicity of the fungal endophyte suggesting its mutually symbiotic relationship with the host. The authors also investigated the antifungal potential of the isolated endophytic strain to ascertain its use as a biocontrol agent. The study shows that P. caribaeo‐quercicola INL3‐2 strain exhibits biocontrol activity against four key fungal phytopathogens that cause significant agronomic and economic losses: Aspergillus flavus, Aspergillus niger, Fusarium solani, and Fusarium oxysporum. Notably, P. caribaeo‐quercicola INL3‐2 strain is highly effective against A. flavus, with an inhibition percentage of 57.63%. In addition, this study investigates the antioxidant activity of P. caribaeo‐quercicola INL3‐2 strain crude extracts using ethyl acetate and methanol as solvents. The results showed that the methanolic fraction of P. caribaeo‐quercicola exhibits potential as an antioxidant agent, with an IC50 value of 171.90 ± 1.15 µg/mL. This investigation is first of its kind and marks the initial report of this fungal basidiomycete, P. caribaeo‐quercicola, as an endophyte associated with a medicinal plant. The findings of this study highlight the potential of P. caribaeo‐quercicola INL3‐2 strain as a dual‐action agent with both biocontrol and antioxidant properties consistent with the medicinal properties of Inula racemosa. This endophytic fungus could be a promising source of natural compounds for use in agriculture, medicine, and beyond.

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“…Bjerkandera sp. endophytic strain was reported by Hafeez et al [32] from a medicinal plant of Kashmir Himalaya. In another study conducted in Hainan province of China, Phellinus sp.…”

Section: Discussionmentioning

confidence: 99%

Evaluating the Biocontrol Efficacy and Antioxidant Potential of Phellinus caribaeo‐quercicola—A First Report Dual‐Action Endophyte From Inula racemosa Hook. F.

Majid,

Wani,

Ganai

2024

J Basic Microbiol

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Section: Medicinal Plants and Their Cultivable Endophyte Resourcesmentioning

confidence: 99%

“…Aconitum heterophyllum is an alkaloid-rich medicinal plant which is widely used in traditional Chinese medicine clinics [ 38 , 39 ]. A total of 328 fungal isolates were found in leaf, stem and root tissues of plants by Hafeez et al, and 12 endophytic fungal species were identified by molecular characterization [ 39 ]. Crocus sativus L. (family Iridaceae) has been widely used as an antimicrobial, antidepressant, digestive, anticancer, and anticonvulsant medicine due to its abundant natural products as well as antioxidant activity [ 40 , 41 ].…”

Section: Medicinal Plants and Their Cultivable Endophyte Resourcesmentioning

confidence: 99%

Cultivable Endophyte Resources in Medicinal Plants and Effects on Hosts

Wang

Zhang

Hao

et al. 2023

Life

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With the increasing demand for medicinal plants and the increasing shortage of resources, improving the quality and yield of medicinal plants and making more effective use of medicinal plants has become an urgent problem to be solved. During the growth of medicinal plants, various adversities can lead to nutrient loss and yield decline. Using traditional chemical pesticides to control the stress resistance of plants will cause serious pollution to the environment and even endanger human health. Therefore, it is necessary to find suitable pesticide substitutes from natural ingredients. As an important part of the microecology of medicinal plants, endophytes can promote the growth of medicinal plants, improve the stress tolerance of hosts, and promote the accumulation of active components of hosts. Endophytes have a more positive and direct impact on the host and can metabolize rich medicinal ingredients, so researchers pay attention to them. This paper reviews the research in the past five years, aiming to provide ideas for improving the quality of medicinal plants, developing more microbial resources, exploring more medicinal natural products, and providing help for the development of research on medicinal plants and endophytes.

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Endophytic Fungal Diversity of Medicinal Plants and Their Role During Stress Response

Chandel,

Kaur,

Kaur

et al. 2024

Ethnopharmacology and OMICS Advances in Medicinal Plants Volume 1

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Molecular characterization of fungal endophyte diversity isolated from Aconitum heterophyllum: a critically endangered medicinal plant of Kashmir Himalaya

Cited by 5 publications

References 64 publications

Evaluating the Biocontrol Efficacy and Antioxidant Potential of Phellinus caribaeo‐quercicola—A First Report Dual‐Action Endophyte From Inula racemosa Hook. F.

Evaluating the Biocontrol Efficacy and Antioxidant Potential of Phellinus caribaeo‐quercicola—A First Report Dual‐Action Endophyte From Inula racemosa Hook. F.

Cultivable Endophyte Resources in Medicinal Plants and Effects on Hosts

Endophytic Fungal Diversity of Medicinal Plants and Their Role During Stress Response

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