Molecular characterization of genotype XIIIb Newcastle disease virus from central India during 2006–2012: Evidence of its panzootic potential

Morla, Sudhir; Shah, Manisha; Kaore, Megha; Kurkure, N. V.; Kumar, Sachin

doi:10.1016/j.micpath.2016.08.005

Cited by 16 publications

(7 citation statements)

References 28 publications

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“…Genotype XIII viruses are widely distributed and have been reported on at least three continents [21, 24, 25, 49–51]. These viruses have historically been classified into five sub-genotypes (XIII a–e) [18, 20, 22–24, 52]. However, some of these studies did not apply objective classification criteria.…”

Section: Discussionmentioning

confidence: 99%

“…These viruses have historically been classified into five subgenotypes (XIII a-e) [18,20,[22][23][24]52]. However, some of these studies did not apply objective classification criteria.…”

Section: Discussionmentioning

confidence: 99%

“…Class II NDV isolates have been detected in both domestic poultry and wild birds worldwide [16,17] and are responsible for at least five ND panzootics [18]. Virulent NDV of genotype XIII have wide geographical distribution and have been reported from Bangladesh, India, Pakistan, Iran, Sweden, Russia, Kazakhstan, Burundi, Tanzania, Zambia, and South Africa [18][19][20][21][22][23][24][25], and are further separated into sub-genotypes.…”

Section: Introductionmentioning

confidence: 99%

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Genetic and biological characterization of Newcastle disease viruses circulating in Bangladesh during 2010–2017: further genetic diversification of class II genotype XIII in Southcentral Asia

Nooruzzaman

Mumu

Kabiraj

et al. 2021

Journal of General Virology

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Newcastle disease virus (NDV) is endemic in Bangladesh and is a major threat to commercial poultry operations. While complete fusion (F) genes are recommended for molecular characterization and classification of NDV isolates, heretofore, only partial F gene data have been available for Bangladeshi NDVs. To this end, we obtained the full-length F gene coding sequences of 11 representative NDVs isolated in Bangladesh between 2010 and 2017. In addition, one of the viruses (MK934289/chicken/Bangladesh/C161/2010) was used in an experimental infection of chickens to establish the viral pathotype and study gross and microscopic lesions. Phylogenetic analysis provided evidence that all studied Bangladeshi isolates belong to genotype XIII.2 of class II NDVs. Six of the viruses were isolated between 2010 and 2017 and grouped together with isolates from neighbouring India during 2013–2016. Another four Bangladeshi isolates (2010–2016) formed a separate monophyletic branch within XIII.2 and showed high nucleotide distance from the isolates from India and the other six Bangladeshi viruses within the sub-genotype; however, none of these groups fulfils all classification criteria to be named as a separate sub-genotype. The eleventh Bangladeshi virus studied here (C162) was genetically more distant from the remaining isolates. It out-grouped the viruses from sub-genotypes XIII.2.1 and XIII.2.2 and showed more than 9.5 % nucleotide distance from all genotype XIII sub-genotypes. This isolate may represent an NDV variant that is evolving independently from the other viruses in the region. The experimental infection in chickens revealed that the tested isolate (C161) is a velogenic viscerotropic virus. Massive haemorrhages, congestion and necrosis in different visceral organs, and lymphoid depletion in lymphoid tissues, typical for infection with velogenic NDV, were observed. Our findings demonstrate the endemic circulation of sub-genotype XIII.2 in Southcentral Asia and further genetic diversification of these viruses in Bangladesh and neighbouring India. This constant evolution of the viruses may lead to the establishment of new genetic groups in the region. Additional historical and prospective virus and surveillance data from the region and neighbouring countries will allow a more detailed epidemiological inference.

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Section: Discussionmentioning

confidence: 99%

“…These viruses have historically been classified into five subgenotypes (XIII a-e) [18,20,[22][23][24]52]. However, some of these studies did not apply objective classification criteria.…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Genetic and biological characterization of Newcastle disease viruses circulating in Bangladesh during 2010–2017: further genetic diversification of class II genotype XIII in Southcentral Asia

Nooruzzaman

Mumu

Kabiraj

et al. 2021

Journal of General Virology

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show abstract

“…Outbreaks of ND in commercial poultry and backyard birds have been reported from many parts of India (7)(8)(9)(10). Vaccines are used regularly in commercial poultry to reduce the devastating consequences of such outbreaks.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Newcastle Disease Virus in Commercial and Backyard Poultry in Haryana, India

et al. 2021

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Newcastle disease virus (NDV) causes Newcastle disease (ND) in poultry. The ND is a highly contagious disease, which is endemic in several countries despite regular vaccination with live or killed vaccines. Studies on NDV in India are mostly targeted toward its detection and characterization from disease outbreaks. A surveillance study was undertaken to determine NDV prevalence throughout the state of Haryana from March 2018 to March 2020 using a stratified sampling scheme. The state was divided into three different zones and a total of 4,001 choanal swab samples were collected from backyard poultry, commercial broilers, and layers. These samples were tested for the M gene of NDV using real-time RT-PCR. Of the 4,001 samples tested, 392 were positive (9.8% apparent prevalence; 95% CI: 8.9–10.8%) for the M gene. Of these 392 M gene positive samples, 35 (8.9%; 95% CI: 6.4–12.3%) were found to be positive based on F gene real-time RT-PCR. Circulation of NDV in commercial and backyard poultry highlights the importance of surveillance studies even in apparently healthy flocks. The information generated in this study should contribute to better understanding of NDV epidemiology in India and may help formulate appropriate disease control strategies for commercial and backyard birds.

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“…The disease was also reported in vulture ( 23 ), emu ( 24 ), etc., which indicated the widespread presence of NDV in different bird species and the threat of these carriers to spread the infection across susceptible host which makes it all more difficult and challenging for the prevention and control. There have been reports of outbreaks of ND in vaccinated and non-vaccinated flocks including backyard poultry from various parts of India including Assam, which is of genotypes II and XIII variant ( 25 – 30 ). The broad circulation of NDV in poultry populations led to a significant genetic diversity of the virus and the constant emergence of NDV variants ( 1 ).…”

Section: Implication Of Nd In Northeastern Indiamentioning

confidence: 99%

Newcastle Disease in Backyard Poultry Rearing in the Northeastern States of India: Challenges and Control Strategies

Puro

Sen

2022

Front. Vet. Sci.

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Molecular characterization of genotype XIIIb Newcastle disease virus from central India during 2006–2012: Evidence of its panzootic potential

Cited by 16 publications

References 28 publications

Genetic and biological characterization of Newcastle disease viruses circulating in Bangladesh during 2010–2017: further genetic diversification of class II genotype XIII in Southcentral Asia

Genetic and biological characterization of Newcastle disease viruses circulating in Bangladesh during 2010–2017: further genetic diversification of class II genotype XIII in Southcentral Asia

Prevalence of Newcastle Disease Virus in Commercial and Backyard Poultry in Haryana, India

Newcastle Disease in Backyard Poultry Rearing in the Northeastern States of India: Challenges and Control Strategies

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