Molecular characterization of native Australian trypanosomes in quokka (Setonix brachyurus) populations from Western Australia

Austen, Jill M.; Paparini, Andrea; Reid, Simon; Friend, J. Anthony; Ditcham, William; Ryan, Una

doi:10.1016/j.parint.2015.12.005

Cited by 5 publications

(4 citation statements)

References 18 publications

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“…Since the late 1980s, PCR of blood or cultured parasites at multiple loci, Sanger sequencing of amplicons and phylogenetic analyses, coupled with traditional and advanced microscopy techniques, have uncovered a broad genetic diversity of Trypanosoma spp. in a range of mammals, including bats, globally (e.g., [ 47 , 49 , 51 , 54 , 64 , 138 ]).…”

Section: Bat Trypanosomesmentioning

confidence: 99%

Diversity and Epidemiology of Bat Trypanosomes: A One Health Perspective

Austen

Barbosa

2021

Pathogens

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Bats (order Chiroptera) have been increasingly recognised as important reservoir hosts for human and animal pathogens worldwide. In this context, molecular and microscopy-based investigations to date have revealed remarkably high diversity of Trypanosoma spp. harboured by bats, including species of recognised medical and veterinary importance such as Trypanosoma cruzi and Trypanosoma evansi (aetiological agents of Chagas disease and Surra, respectively). This review synthesises current knowledge on the diversity, taxonomy, evolution and epidemiology of bat trypanosomes based on both molecular studies and morphological records. In addition, we use a One Health approach to discuss the significance of bats as reservoirs (and putative vectors) of T. cruzi, with a focus on the complex associations between intra-specific genetic diversity and eco-epidemiology of T. cruzi in sylvatic and domestic ecosystems. This article also highlights current knowledge gaps on the biological implications of trypanosome co-infections in a single host, as well as the prevalence, vectors, life-cycle, host-range and clinical impact of most bat trypanosomes recorded to date. Continuous research efforts involving molecular surveillance of bat trypanosomes are required for improved disease prevention and control, mitigation of biosecurity risks and potential spill-over events, ultimately ensuring the health of humans, domestic animals and wildlife globally.

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Section: Bat Trypanosomesmentioning

confidence: 99%

Diversity and Epidemiology of Bat Trypanosomes: A One Health Perspective

Austen

Barbosa

2021

Pathogens

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“…As a consequence, there has been a recent surge in studies on trypanosomes occurring in wildlife with eight molecularly determined species and additional incompletely identified species infecting platypus, a wide range of marsupial species and native rats and mice (Averis et al 2009;McInnes et al 2009). Evidence includes mixed infections (McInnes et al 2011a(McInnes et al , 2011bThompson et al 2013;Godfrey et al 2018) multiple host species (Austen et al 2009(Austen et al , 2015McInnes et al 2011aMcInnes et al , 2011b, novel genotypes (Austen et al 2009(Austen et al , 2015(Austen et al , 2016Paparini et al 2014), morphological polymorphism (Thompson et al 2013) and potential pathogenesis in endangered species (McInnes et al 2011a(McInnes et al , 2011bThompson et al 2013Thompson et al , 2014aThompson et al , 2014bAusten et al 2015;Godfrey et al 2018). Although no life cycles are known, molecular detection of trypanosomes in an aquatic leech suggest that these may be vectors for T. binneyi and related genotypes (Paparini et al 2014).…”

Section: Trypanosomamentioning

confidence: 99%

Wildlife parasitology in Australia: past, present and future

Spratt

Beveridge

2018

Aust. J. Zool.

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Wildlife parasitology is a highly diverse area of research encompassing many fields including taxonomy, ecology, pathology and epidemiology, and with participants from extremely disparate scientific fields. In addition, the organisms studied are highly dissimilar, ranging from platyhelminths, nematodes and acanthocephalans to insects, arachnids, crustaceans and protists. This review of the parasites of wildlife in Australia highlights the advances made to date, focussing on the work, interests and major findings of researchers over the years and identifies current significant gaps that exist in our understanding. The review is divided into three sections covering protist, helminth and arthropod parasites. The challenge to document the diversity of parasites in Australia continues at a traditional level but the advent of molecular methods has heightened the significance of this issue. Modern methods are providing an avenue for major advances in documenting and restructuring the phylogeny of protistan parasites in particular, while facilitating the recognition of species complexes in helminth taxa previously defined by traditional morphological methods. The life cycles, ecology and general biology of most parasites of wildlife in Australia are extremely poorly understood. While the phylogenetic origins of the Australian vertebrate fauna are complex, so too are the likely origins of their parasites, which do not necessarily mirror those of their hosts. This aspect of parasite evolution is a continuing area for research in the case of helminths, but remains to be addressed for many other parasitic groups.

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“…copemani parece ser um tanto ubíquo, pois tem sido identificado infectando diferentes espécies de marsupiais australianos (coalas, vombates, quokkas, entre outros) Austen et al, 2016). Igualmente, T. vegrandis tem sido encontrado em uma grande variedade de marsupiais, carnívoros e também morcegos (Thompson et al, 2013;Barbosa et al, 2016b).…”

Section: Clado T Copemaniunclassified

“…Sequências do gene ribossômico têm sido bastante utilizadas para inferir relações filogenéticas entre organismos da classe Kinetoplastida Simpson et al, 2006;Lukes et al, 2014;Cavalier-Smith, 2016), para estabelecer os principais grupos naturais dentro da família Trypanosomatidae Merzlyak et al, 2001;Cavazzana et al, 2010) e para a identificação de gêneros, espécies, linhagens e genótipos dentro do gênero Trypanosoma (Maia da Silva et al, 2004;Rodrigues et al, 2006;Hamilton et al, 2007;Ferreira et al, 2007Ferreira et al, , 2008Viola et al 2008;Lemos et al, 2015;Austen et al, 2016). …”

Section: Gene Ribossômico (Rdna)unclassified

Spliced Leader (SL) RNA: análises de genes e regiões intergênicas com aportes na filogenia, taxonomia e genotipagem de <i>Trypanosoma</i> spp. de todas as classes de vertebrados.

Alvarez¹

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Molecular characterization of native Australian trypanosomes in quokka (Setonix brachyurus) populations from Western Australia

Cited by 5 publications

References 18 publications

Diversity and Epidemiology of Bat Trypanosomes: A One Health Perspective

Diversity and Epidemiology of Bat Trypanosomes: A One Health Perspective

Wildlife parasitology in Australia: past, present and future

Spliced Leader (SL) RNA: análises de genes e regiões intergênicas com aportes na filogenia, taxonomia e genotipagem de <i>Trypanosoma</i> spp. de todas as classes de vertebrados.

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