2009
DOI: 10.1099/jmm.0.007567-0
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Molecular characterization of Staphylococcus epidermidis strains isolated from a teaching hospital in Shanghai, China

Abstract: Staphylococcus epidermidis is a leading cause of hospital-acquired infections, mostly associated with the use of medical devices in seriously ill or immunocompromised patients. Currently, the clonal characteristics of S. epidermidis in the hospital environment in China are unknown; neither is it known why these sequence types are easily disseminated in the hospital setting. In this study, multilocus sequence typing (MLST) was employed for the clonal analysis of 80 S. epidermidis isolates collected from patient… Show more

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Cited by 83 publications
(94 citation statements)
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“…About 83.33% of these isolates were carriers of IS256 and equally of SCCmec types II and III. Therefore, our data support the data of Li et al [49] and Iorio et al [50]. Our ST23 isolates, similar to those of Iorio et al [50], were exclusively ica-positive.…”
Section: Multilocus Sequence Typingsupporting
confidence: 82%
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“…About 83.33% of these isolates were carriers of IS256 and equally of SCCmec types II and III. Therefore, our data support the data of Li et al [49] and Iorio et al [50]. Our ST23 isolates, similar to those of Iorio et al [50], were exclusively ica-positive.…”
Section: Multilocus Sequence Typingsupporting
confidence: 82%
“…An explanation for the divergent results may be the study population; the above-stated groups compared isolates from patients and healthy individuals, whereas our study population and that of Li et al [49] included only hospitalized patients.…”
Section: Multilocus Sequence Typingmentioning
confidence: 49%
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“…These differences are probably the result of an adaptation to the significant pressure caused by the intensive use of antibiotics in hospitals, as has been particularly demonstrated by others for ␤-lactams and quinolones (30). Li et al (11), for example, observed 96% methicillin resistance among nosocomial S. epidermidis isolates in China.…”
Section: Discussionmentioning
confidence: 99%