Molecular cloning and modeling of the Tp53-induced glycolysis and apoptotic regulator (TIGAR) from the Pacific white shrimp Litopenaeus vannamei and its expression in response to hypoxia

Camacho‐Jiménez, Laura; Félix-Portillo, Monserrath; Nuñez-Hernandez, Dahlia M.; Yépiz-Plascencia, Glória

doi:10.1016/j.fsi.2019.08.003

Cited by 6 publications

(2 citation statements)

References 36 publications

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“…Interestingly, Tp53 induces glycolysis and apoptotic regulator (TIGAR), a protein similar to fructose‐2,6‐bisphosphatase, which exerts a pro‐survival role that promotes the tolerance of L . vannamei to hypoxia 118 . Hypoxia is a common source of oxidative stress, 119 and reduced expression of antioxidant proteins (eg SOD and GPx) is positively regulated by p53, which is a potential mechanism through which L .…”

Section: Signalling Pathways Affacted By Hypoxic Stress In Crustaceanmentioning

confidence: 99%

“…induces glycolysis and apoptotic regulator (TIGAR), a protein similar to fructose-2,6-bisphosphatase, which exerts a pro-survival role that promotes the tolerance of L. vannamei to hypoxia. 118 Hypoxia is a common source of oxidative stress, 119 and reduced expression of antioxidant proteins (eg SOD and GPx) is positively regulated by p53, which is a potential mechanism through which L. vannamei promotes its survival under oxidative stress. 120 A recent study confirmed that mitochondrial SOD functions in L. vannamei preventing apoptosis in response to hypoxia.…”

Section: Hypoxia-induced Apoptotic Signalling In Crustaceansmentioning

confidence: 99%

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Role of hypoxia in the behaviour, physiology, immunity and response mechanisms of crustaceans: A review

Zheng

Zhao

et al. 2021

Reviews in Aquaculture

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Crustaceans are often exposed to hypoxic stress in intensive aquaculture systems. Such stress leads to physiological, behavioural and biochemical changes, which can cause various metabolic disorders or even death. Crustacean response mechanisms to hypoxia stress are known to be complex, with their regulation involving multiple genes. In this review, after briefly exploring some known causes of hypoxic stress in aquaculture systems, we discuss the physiological adaptation strategies used by crustaceans in response to hypoxia and summarise recent information regarding the effects of hypoxia on the behaviour, survival, antioxidant ability, metabolic processes and innate immunity of crustaceans. In addition, we give particular emphasis to the known molecular mechanisms underlying hypoxia related to the hypoxia‐inducible factor 1 (HIF‐1) signalling pathway, the adenosine 5′‐monophosphate‐activated protein kinase signalling (AMPK) pathway, and apoptosis. Practically, it is clear that multiple measures need to be taken to prevent and regulate the adverse effects of hypoxic stress in intensive aquaculture systems, including development of hypoxia‐resistant breeds and nutritional regulation techniques. Overall, this review provides a theoretical basis for understanding the molecular mechanisms underlying hypoxic stress in crustaceans, while making conceptual connections with data from related study areas in other species.

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Section: Signalling Pathways Affacted By Hypoxic Stress In Crustaceanmentioning

confidence: 99%

Section: Hypoxia-induced Apoptotic Signalling In Crustaceansmentioning

confidence: 99%

Role of hypoxia in the behaviour, physiology, immunity and response mechanisms of crustaceans: A review

Zheng

Zhao

et al. 2021

Reviews in Aquaculture

View full text Add to dashboard Cite

show abstract

The combination of hypoxia and high temperature affects heat shock, anaerobic metabolism, and pentose phosphate pathway key components responses in the white shrimp (Litopenaeus vannamei)

González-Ruiz

Leyva‐Carrillo

Peregrino‐Uriarte

et al. 2023

Cell Stress and Chaperones

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Differential regulation of glucolipid metabolism by acute hypoxia in gibel carp (Carassius gibelio) strains

Wu,

Li,

Chen

et al. 2024

Aquaculture Reports

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Molecular cloning and modeling of the Tp53-induced glycolysis and apoptotic regulator (TIGAR) from the Pacific white shrimp Litopenaeus vannamei and its expression in response to hypoxia

Cited by 6 publications

References 36 publications

Role of hypoxia in the behaviour, physiology, immunity and response mechanisms of crustaceans: A review

Role of hypoxia in the behaviour, physiology, immunity and response mechanisms of crustaceans: A review

The combination of hypoxia and high temperature affects heat shock, anaerobic metabolism, and pentose phosphate pathway key components responses in the white shrimp (Litopenaeus vannamei)

Differential regulation of glucolipid metabolism by acute hypoxia in gibel carp (Carassius gibelio) strains

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