2006
DOI: 10.1007/s10858-006-9006-0
|View full text |Cite
|
Sign up to set email alerts
|

Molecular conformations of a disaccharide investigated using NMR spectroscopy

Abstract: The molecular structure of alpha-L-Rhap-(1--> 2)-alpha-L-Rhap-OMe has been investigated using conformation sensitive NMR parameters: cross-relaxation rates, scalar 3J(CH) couplings and residual dipolar couplings obtained in a dilute liquid crystalline phase. The order matrices of the two sugar residues are different, which indicates that the molecule cannot exist in a single conformation. The conformational distribution function, P(phi, psi) related to the two glycosidic linkage torsion angles phi and psi was … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

0
20
0

Year Published

2008
2008
2016
2016

Publication Types

Select...
7
1
1

Relationship

4
5

Authors

Journals

citations
Cited by 26 publications
(20 citation statements)
references
References 36 publications
0
20
0
Order By: Relevance
“…In the isotropic liquid only the J-couplings are observable, whereas the direct dipolar interactions are averaged (by the rapid molecular tumbling) to zero. [44][45][46][47][48][49][50][51] We have used trajectories generated in the MD simulations carried out in the previous study 5 for interpretation of experimental herein acquired NMR parameters and analyses of the membrane-TRH interactions. In principle, there are two NMR spectroscopy techniques to study anisotropic dipolar interactions: a) conventional high-resolution NMR where a weakly ordered solvent [37][38][39] is used, and b) solid-state NMR.…”
Section: Introductionmentioning
confidence: 99%
“…In the isotropic liquid only the J-couplings are observable, whereas the direct dipolar interactions are averaged (by the rapid molecular tumbling) to zero. [44][45][46][47][48][49][50][51] We have used trajectories generated in the MD simulations carried out in the previous study 5 for interpretation of experimental herein acquired NMR parameters and analyses of the membrane-TRH interactions. In principle, there are two NMR spectroscopy techniques to study anisotropic dipolar interactions: a) conventional high-resolution NMR where a weakly ordered solvent [37][38][39] is used, and b) solid-state NMR.…”
Section: Introductionmentioning
confidence: 99%
“…conformational maps) using a particular level of theory, [7][8][9][10][11][12][13][14][15][16][17][18] NMR-NOE based maps, [19][20][21][22] and MD scatter plots, [23][24][25][26][27] there has been little effort at creating generalized carb-Rama plots. In 1999 and 2002, Wormald and coworkers surveyed available NMR and X-ray data of oligosaccharides and glycopeptides.…”
Section: Introductionmentioning
confidence: 99%
“…4) and 2D NMR (HSQC, HMBC) spectra (Fig. 5) and by further comparison with those of lactulose and to the literatures (Landersjo et al, 2006;Taubert, Konschin, & Sundholm, 2005).…”
Section: Resultsmentioning
confidence: 79%