Molecular detection and genomic characteristics of bovine kobuvirus from dairy calves in China

Li, Huiping; Tang, Cheng; Yue, Hua

doi:10.1016/j.meegid.2019.103939

Cited by 13 publications

(22 citation statements)

References 15 publications

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“…Similar to findings reported byLi et al, 2019, these 121 strains form 8 lineages. BKV strains from UK belongs to two lineages (1 and 5), whereas BKV strains from China are lineage 2, 3, 4, 6, 7 and 8.…”

supporting

confidence: 83%

“…positive out of 49) (Park et al, 2010). Two studies were also performed in China (Chang et al, 2014;Li et al, 2019) (Table 1). The first study reported detection of BKV in 58 of 166 faecal samples collected in diarrhoeic dairy cows (Chang et al, 2014).…”

Section: Rt-pcr Detection Of Bkv In Asian Countriesmentioning

confidence: 99%

“…In 2019, our group first detected BKV in a faecal sample of 10-to 14-day-old diarrhoeic calves in the United States using metagenomics sequencing on MiSeq (Wang et al, 2020 (Li et al, 2019). In the present review, a total of 121 VP1 genes available at GenBank were included for alignment and phylogenetic tree construction.…”

Section: Rt-pcr Detection Of Bkv In American Countriesmentioning

confidence: 99%

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Bovine kobuvirus—A comprehensive review

Hao

Chen

Bailey

et al. 2020

Transbound Emerg Dis

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Diarrhoea is a leading cause of calf mortality in US cattle herds, resulting in significant economic losses to cattle producers. Calves with diarrhoea are often <1 month of age. Infectious causes of calf diarrhoea include viral, bacterial and protozoal pathogens. Diagnostic tests are routinely utilized for detection of common viruses such as bovine rotavirus (BRV), bovine coronavirus (BCoV) and bovine viral diarrhoea virus (BVDV). However, a review of laboratory test results generated between 1 January 2016 and 21 August 2019 at the University of Illinois Veterinary Diagnostic Laboratory (VDL) showed that these three viruses (BRV, BCoV and BVDV) were detected in approximately 30% of calves with diarrhoea, including animals with histopathology changes that were suggestive of viral involvement. These results suggest that other unidentified viral pathogens may be involved in calf diarrhoea. Recently, we reported identification of bovine kobuvirus (BKV) in diarrhoeic calves in the United States and added evidence that BKV might be associated with diarrhoea in cattle (Wang et al., 2020). Herein, we review taxonomy and genome organization, detection of BKV in different countries and genomic characterization.

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supporting

confidence: 83%

Section: Rt-pcr Detection Of Bkv In Asian Countriesmentioning

confidence: 99%

Section: Rt-pcr Detection Of Bkv In American Countriesmentioning

confidence: 99%

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Bovine kobuvirus—A comprehensive review

Hao

Chen

Bailey

et al. 2020

Transbound Emerg Dis

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“…The exact role of BKV in the pathogenesis of diarrhea is not fully elucidated; however, the detection rate of BKV in fecal samples from calves with clinical signs is higher when compared with animals without clinic signs, reinforcing the participation of BKV in the pathogenesis of diarrhea [35]. In this study, BKV was identified in mixed infections, and similar findings were previously described [21,36], suggesting that the occurrence of this virus may be associated with the concomitant presence of other diarrheic pathogens of cattle.…”

Section: Introductionmentioning

confidence: 99%

Severe outbreak of bovine neonatal diarrhea in a dairy calf rearing unit with multifactorial etiology

et al. 2021

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This study describes the etiological diversity observed in a severe neonatal diarrhea outbreak with morbidity and mortality rates of 80 and 20%, respectively, with detection of mixed infections with viral, bacterial, and protozoan disease agents in a dairy calf rearing unit. Diarrheic fecal samples were collected from eight 5 to 18 days of age calves and were submitted to the investigation of the presence of rotavirus A (RVA), bovine coronavirus (BCoV), bovine kobuvirus (BKV), bovine viral diarrhea virus 1 and 2 (BVDV-1 and BVDV-2), enteropathogenic Escherichia coli (ETEC), Salmonella sp., and Cryptosporidium spp. Fragments of the small intestine of one calf with diarrhea that spontaneously died were submitted for histopathological analyses. The most frequent infectious agent detected in diarrheic fecal samples was BKV (8/8-100%), followed by RVA (5/8-62.5%), BVDV (5/8-62.5%), Cryptosporidium parvum (5/8-62.5%), ETEC (4/8-50%), and Cryptosporidium ryanae (1/8-12.5%). These etiological agents were found in mixed infections with two or more pathogens per diarrheic fecal sample. The association of viral and protozoan pathogens was the most frequently identified (37.5%) in these samples, followed by viral and bacterial (25%); viral, bacterial, and protozoan (25%); and only viral agents (12.5%). BCoV and Salmonella sp. were not identified in the diarrheic fecal samples analyzed. Additionally, histopathology of the small intestine diagnosed chronic lymphocytic enteritis. In conclusion, in calf rearing units, the adoption and strict monitoring of health management practices are critical to the success of this calf creation system.

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“…Kobuviruses have a wide host range worldwide, including humans, dogs, cats, pigs, cattle, goats, sheep, bats, rats, and mice [1,4,[8][9][10]. The mouse kobuvirus was detected in Peromyscus crinitus and Peromyscus maniculatus mice in the USA in 2011 [11].…”

Section: Introductionmentioning

confidence: 99%

Kobuviruses carried by Rattus norvegicus in Guangdong, China

You

Zhang

et al. 2020

BMC Microbiol

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Background: Murine kobuviruses (MuKV) are newly recognized picornaviruses first detected in murine rodents in the USA in 2011. Little information on MuKV epidemiology in murine rodents is available. Therefore, we conducted a survey of the prevalence and genomic characteristics of rat kobuvirus in Guangdong, China.Results: Fecal samples from 223 rats (Rattus norvegicus) were collected from Guangdong and kobuviruses were detected in 12.6% (28) of samples. Phylogenetic analysis based on partial 3D and complete VP1 sequence regions showed that rat kobuvirus obtained in this study were genetically closely related to those of rat/mouse kobuvirus reported in other geographical areas. Two near full-length rat kobuvirus genomes (MM33, GZ85) were acquired and phylogenetic analysis of these revealed that they shared very high nucleotide/amino acids identity with one another (95.4%/99.4%) and a sewage-derived sequence (86.9%/93.5% and 87.5%/93.7%, respectively). Comparison with original Aichivirus A strains, such human kobuvirus, revealed amino acid identity values of approximately 80%. Conclusion: Our findings indicate that rat kobuvirus have distinctive genetic characteristics from other Aichivirus A viruses. Additionally, rat kobuvirus may spread via sewage.

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Molecular detection and genomic characteristics of bovine kobuvirus from dairy calves in China

Cited by 13 publications

References 15 publications

Bovine kobuvirus—A comprehensive review

Bovine kobuvirus—A comprehensive review

Severe outbreak of bovine neonatal diarrhea in a dairy calf rearing unit with multifactorial etiology

Kobuviruses carried by Rattus norvegicus in Guangdong, China

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