“…The BIV genome, similar to human immunodeficiency virus (HIV) and other lentiviruses, contains the structural genes gag, pol, env and several accessory genes tat, rev, vif, vpw, vpy, and tmx. However, although some studies on BIV are focused on tat (Guo et al, 2013), vif (Zhang et al, 2014) rev (Gomez Corredor and Archambault, 2009;Gomez Corredor and Archambault, 2012) and others (Albernaz et al, 2015;Liu et al, 2015), very scarce attention has been paid to env. The Env of BIV is composed of two subunits: gp100, a surface subunit (SU) that binds host cell receptors, and gp45, a transmembrane subunit (TM) that ultimately inserts into the host cell membrane and promotes the fusion.…”