Molecular detection of Rickettsia sp. genotype RF2125 from household dogs in the central highlands of Vietnam

Nguyen, Trong Van; Nguyen, Hieu Quoc; Stenos, John; Nguyen, Thai Van; Ng-Nguyen, Dinh

doi:10.1016/j.rvsc.2023.104989

Cited by 1 publication

(1 citation statement)

References 31 publications

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“…R. asembonensis was first identified in Kenya in 2013, and since then, multiple studies have reported its global detection in a variety of arthropods collected from domestic, peri-domestic, and wildlife animals [ 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 ]. Although its pathogenicity and role as a human pathogen has not yet been elucidated, its detection in both human [ 10 , 11 , 12 , 13 ] and animal [ 14 , 15 , 16 ] specimens suggests a potential public health threat.…”

Section: Introductionmentioning

confidence: 99%

Rickettsia asembonensis Isolated from Four Human Cases with Acute Undifferentiated Febrile Illness in Peru

Loyola,

Palacios-Salvatierra,

Cáceres-Rey

et al. 2024

Pathogens

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Rickettsioses, often underreported, pose public health challenges. Rickettsia asembonensis is a potential emerging pathogen that was previously detected in humans, animals, and a variety of arthropods. While its pathogenicity in humans remains unclear, it poses a potential public health threat. Here, we present an extended epidemiological, diagnostic, and genetic analysis of the information provided in a preliminary report on the investigation of rickettsiae in Peru. In particular, we report the detection of R. asembonensis in blood specimens collected from four human patients with an acute undifferentiated fever of a seven- to nine-day duration, all of whom tested negative for other vector-borne pathogens. Additionally, we describe the replicative capacity of the R. asembonensis isolates in cell cultures.

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