Molecular Diagnostics

Pusterla, Nicola; Leutenegger, Christian M.; Crossley, Beate; Hietela, Sharon

doi:10.1016/b978-0-323-55445-9.00029-x

Cited by 1 publication

(1 citation statement)

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“…A negative result does not exclude the diagnosis, as intermittent levels of bacteremia could produce false-negative results. The PCR supports diagnosis particularly in the earliest and latest stages of the disease, when the number of parasites is too low to be detected by microscopy analysis [ 34 ].…”

Section: Discussionmentioning

confidence: 99%

A Case Study of Photosensitivity Associated with Anaplasma spp. Infection in Cattle

Anton

Solcan

2022

Animals

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Anaplasma infection has not previously been reported as a cause of photosensitization. This case presents a five-year-old Holstein cow in her fifth month of gestation with skin injury of nonpigmented areas clearly delimited from adjacent unaffected pigmented skin. Specific lesions included alopecia, localized oedema, desquamation erythema, serous exudation, thick detached skin, fissures, crusting, and necrosis, indicating photodermatitis. Hematological abnormalities were leukocytosis with neutrophilia and normocytic hypochromic anemia. Based on a hemoparasitic examination of blood smears, the organism Anaplasma spp. was observed within the red blood cells. Biochemical analyses revealed increased serum liver enzyme activity associated with hepatocellular damage and cholestasis. This cow was RT-PCR positive for Anaplasma spp. infection. After treatment with oxytetracycline started, its condition improved within 24 h, and it recovered completely within 30 days. In this case, the underlying pathogenic mechanism of Anaplasma spp. infection facilitated the impairment of bile flow and liver function, resulting in hepatogenous photosensitization.

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Section: Discussionmentioning

confidence: 99%