Molecular diversity of 23 Y-chromosome short tandem repeat loci in the population of Tuzla Canton, Bosnia and Herzegovina

Abstract

These results could be used as an additional investigation of the genetic relationship between the regional populations in Bosnia and Herzegovina and neighbouring human populations, as well as for further human population and forensic genetics studies.

Contemporary population genetics data for 23 Y-STR loci in the general Bosnian-Herzegovinian population

“…More precisely, in a sample of 480 Y chromosomes, 454 haplotypes were unique. In a previous study of the local Tuzla Canton (B&H) population, all 100 haplotypes were unique (Babic et al, 2017), while in the local Sarajevo Canton (B&H) population, 98 samples had unique haplotypes, while one haplotype was repeated twice (Kovacevic et al, 2013), with both studies performed using the same Y-STR loci that were used in our study. For comparison, a study of the general Bosnian-Herzegovinian population on 100 typed over 12 Y-STR loci produced only 81 different haplotypes, including 71 unique (Cenanovic et al, 2010).…”

“…Just like the rest of the region, B&H is a very interesting area for the population studies, since the country is a home to several partially isolated indigenous populations, in addition to being found at the crossroads between the Middle East and Western Europe. Due to that, country-level studies on autosomal and linage markers (Marjanovic et al, 2004a;Marjanovic et al, 2005;Kovacevic et al, 2013), as well as the studies of characteristic subpopulations, such as the Sarajevo Canton (Cenanovic et al, 2010) and the Tuzla Canton (Babic et al, 2017) populations, gained the attention of the research community in the past. In addition, studies of isolated populations inhabiting highaltitude areas significantly contributed to the knowledge of the molecular diversity of genetic markers in B&H (Marjanovic et al, 2004b).…”

An ethnic genetics – case study of B&H: facts, fallacies and myths

“…The largest dataset (N = about 20,000) was collected for the purpose of DNA profiling of the remains of war victims and consisted of STR profiles of exhumed victims and reference profiles of their surviving relatives. Genetic distance among B&H local and metapopulations, with regard to several (nuclear and mitochondrial) genetic markers was extensively studied by numerous authors (Marjanović et al 2005a, 2005b, Battaglia et al 2009, Pojskic et al 2013a, 2013b, Ahmić et al 2014, Kapur-Pojskic et al 2014, Kovacevic et al, 2014, Sarac et al, 2014, Carreras-Torres et al, 2016, Babić et al, 2017, Ahmic et al, 2018. Since 2016, contemporary research has gradually been expanding into the field of omic technologies.…”