Molecular engineering of a colorimetric two-photon fluorescent probe for visualizing H2S level in lysosome and tumor

Mitochondria-Targeted Red-Emission Fluorescent Probe for Ultrafast Detection of H2S in Food and Its Bioimaging Application

“…A good linear correlation was exhibited by plotting the relationship between the HS – concentration and the fluorescence intensity of emission at 608 nm ( R 2 = 0.997). The detection limit was as low as 356 nM in terms of the limit of detection (LOD) = 3δ/ k (Figure ), , which is lower than the threshold of H 2 S (1.47 μM) permitted in drinking water set by the World Health Organization (WHO)…”

A highly sensitive and selective fluorescent probe for tracking hydrogen sulfide in red wine

“…Besides, the limit of detection (LOD) of LODNBS for H 2 S was calculated to be 72 nM by the 3σ method (LOD=3σ/K), which is much lower than the concentration of physiological H 2 S in human blood (35–80 μM), [34] suggesting that LODNBS can detect H 2 S with high sensitivity. Furthermore, according to the comparison of LODNBS with other reported fluorescent probes in the literature (Table 1), the LOD of LODNBS for H 2 S was lower than other published probes [35–40] . The time dependent fluorescence spectra of LODNBS (20 μM) to H 2 S (100 μM) were then conducted.…”

Visual detection of S2− with a paper‐based fluorescence sensor coated with CdTe quantum dots via headspace sampling

“…More importantly, S 2− can cause severe effects on the human nervous system, leading to various severe diseases such as respiratory paralysis, liver cirrhosis or Down's syndrome, [ 3,4 ] so efficient and effective monitoring of S 2− using rapid and sensitive methodology is very important. Furthermore, aqueous protonation of S 2− can lead to the easy formation of hydrogen sulfide (H 2 S) inclined to be released to the air, which is recognized as one of the most toxic air pollutants as well as the neurotransmitter in biological processes, [ 2,5–8 ] causing many diseases such as diabetes, blood poisoning and liver cirrhosis. [ 9,10 ] Therefore, environmental exposure to H 2 S should be strictly monitored, including that evolved from aqueous S 2−.…”

“…However, these often require complicated procedures and intricate precursors, especially organic ones, for preparing certain FL probes for sensing particular targets and, in many cases, the obtained probes still suffer from low solubility in aqueous phase, poor biocompatibility and photobleaching during the sensing process. [ 8,27,28 ] In contrast, inorganic quantum dots (QDs) have unique optical properties including high quantum yields, photostability and biocompatibility, and broad absorption spectra with narrow emission spectra, thereby driving tremendous attentions as the probes for sensing diverse organic and inorganic analytes including S 2− and/or H 2 S. [ 29–31 ] During recent years, QD‐coated paper has attracted increasing attentions as new analytical device that benefited from its simplicity, rapidness, cost–effectiveness, and visual output. [ 32,33 ] However, the interference from liquid‐phase sample matrices should not be ignored when using paper‐based sensors, especially in the analysis of real samples.…”