Molecular epidemiology and antimicrobial resistance of Salmonella isolates from broilers and pigs in Thailand

Phongaran, Dusadee; Khang-Air, Seri

doi:10.14202/vetworld.2019.1311-1318

Cited by 35 publications

(47 citation statements)

References 34 publications

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“…One study conducted among hogs in Vietnam reported that 36.7% of Salmonella isolates were resistant to trimethoprim/sulfamethoxazole and only 41.3% to ampicillin [27]. On the other hand, low rates of resistance (< 5%) to ESC and cipro oxacin were reported in both studies [13,27], while this present study reported rates which were slightly higher (< 10%).…”

Section: Discussioncontrasting

confidence: 77%

“…The increasing prevalence of MDR Salmonella in livestock animals has been widely reported [13,15,27,28] and is mainly attributed to the inappropriate use of antimicrobial agents in veterinary medicine [18,19]. We report that 89.4% of S. enterica isolated from slaughtered pork were non-susceptible to at least one antimicrobial agent and 13.5% were MDR.…”

Section: Discussionmentioning

confidence: 87%

“…In this study, multidrug resistance was observed in 13.5% of S. enterica isolates. Reports of (multidrugresistant) MDR Salmonella isolated from hogs in other Southeast Asian countries are higher (30-40%) (13,27). In other countries, even higher rates (70-80%) of MDR Salmonella isolated from pork and the pork production chain were observed [15,28].…”

Section: Discussionmentioning

confidence: 97%

“…In this study, non-susceptibilities to ampicillin and trimethoprim/sulfamethoxazole were observed in 71.9% and 70.8% of S. enterica, respectively. Phongaran et al [13] reported that 69.0% of Salmonella isolated from hogs in Thailand were resistant to ampicillin. However, in this study, only 35.7% were resistant to trimethoprim/sulfamethoxazole.…”

Section: Discussionmentioning

confidence: 99%

“…These genes are broadly distributed worldwide and are commonly found in association with genes encoding for ß-lactamases [8][9][10][11]. Consequently, bla and qnr genes have been increasingly found in bacteria isolated from livestock animals [8,9,[12][13][14][15][16][17]. If motile, resistance determinants may accelerate the spread of AMR when these are taken up by non-pathogenic or pathogenic bacteria alike.…”

Section: Introductionmentioning

confidence: 99%

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Antimicrobial Susceptibility and Prevalence of bla and qnr Genes in Salmonella Enterica Isolated from Slaughtered Pork

Calayag

Widmer

Rivera

2021

Preprint

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Background: Salmonella enterica is known as one of the most common foodborne pathogens worldwide. While salmonellosis is usually self-limiting, severe infections may require antimicrobial therapy. However, increasing resistance of Salmonella to antimicrobials, particularly fluoroquinolones and cephalosporins, is of utmost concern. The present study aimed to investigate the antimicrobial susceptibility of S. enterica isolated from pork, the major contributor in Philippine livestock production.Results: Our results show that 61.2% of the isolates carried antimicrobial resistance genes qnrS and blaTEM. While qnrA (12.9%) and qnrB (39.3%) were found less frequently, co-carriage of blaTEM and one to three qnr subtypes was observed in 45.5% of the isolates. Co-carriage of blaTEM and blaCTX-M was also observed in 3.9% of the isolates. Antimicrobial susceptibility testing revealed that majority of the isolates were non-susceptible to ampicillin and trimethoprim/sulfamethoxazole, and 13.5% of the isolates were multidrug-resistant.Conclusions: High prevalence rates of S. enterica carrying antimicrobial resistance genes (ARG), specifically the presence of isolates co-carrying resistance to both ß-lactams and fluoroquinolones, raise a concern on antimicrobial use in the Philippine hog industry and on possible transmission of ARG to other bacteria.

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Section: Discussioncontrasting

confidence: 77%