Molecular epidemiology of Babesia vogeli in dogs from the southeastern region of Rio de Janeiro, Brazil

Paulino, Patrícia Gonzaga; Pires, Marcus Sandes; Silva, Cláudia Bezerra da; Peckle, Maristela; Costa, Renata Lins da; Vitari, Gabriela Lopes Vivas; Abreu, Ana Paula Martinez de; Massard, Carlos Luiz; Santos, Huarrisson Azevedo

doi:10.1016/j.vprsr.2018.06.004

Cited by 7 publications

(7 citation statements)

References 22 publications

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“…These authors observed that newly weaned young dogs were more susceptible to disease due to the stress of adapting to food and the environment. Our results also corroborate those of Paulino et al (2018), who found that animals under five years of age were more likely to test positive for B. vogeli DNA.…”

Section: Discussionsupporting

confidence: 91%

Occurrence of tick-borne pathogens in dogs in a coastal region of the state of Ceará, northeastern Brazil

Fonsêca

Oliveira

Jorge

et al. 2022

Rev. Bras. Parasitol. Vet.

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The aim of this study was to determine the occurrence of tick-borne pathogens (Ehrlichia canis, Babesia vogeli, Hepatozoon spp. and Rickettsia spp.) in dogs in Vila de Jericoacoara, coastal region of Ceará, Brazil. Blood samples were collected from 153 animals and analyzed using molecular and serological methods. Sixty animals were found to be infected or exposed to at least one of the pathogens studied. Babesia vogeli was the most prevalent pathogen (15%), followed by E. canis (13.7%) and Hepatozoon spp. (11.8%), which was identified as Hepatozoon canis through sequencing. Twenty dogs (13%) were seroreactive to Rickettsia spp. Rhipicephalus sanguineus sensu lato was observed on 11.8% of the animals. There were associations between age (< 3 years old) and positivity for B. vogeli, and between habitation (stray dogs) and positivity for H. canis. There were also associations between anemia and infection with H. canis, and between leukopenia and exposure to Rickettsia spp. No association was detected between clinical alterations and infection with or exposure to the pathogens studied. The results confirmed that pathogens of veterinary importance are circulating in northeastern Brazil and showed that dogs are exposed to Rickettsia species with zoonotic potential, thus indicating a need for vector control measures.

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Section: Discussionsupporting

confidence: 91%

Occurrence of tick-borne pathogens in dogs in a coastal region of the state of Ceará, northeastern Brazil

Fonsêca

Oliveira

Jorge

et al. 2022

Rev. Bras. Parasitol. Vet.

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“…This may be due to the shorter time of circulation of B. vogeli in the blood of infected animals. Epidemiological data from previous studies demonstrated that B. vogeli is highly prevalent in Brazil, with up to 8.2% molecularly positive dogs in Pernambuco (Ramos et al 2010 ; Dantas-Torres et al 2021 ), 8.0% in São Paulo (O’Dwyer et al 2009 ), 10.0% in Paraíba (Rotondano et al 2015 ), 15.0% in Ceará (Fonsêca et al 2022 ), 30.6% in Minas Gerais (Barbosa et al 2020 ) and 14.1% in Rio de Janeiro (Paulino et al 2018 ; Camilo et al 2021 ). Conversely, H. canis has been reported with lower prevalence (i.e., 0.4% to 5.4%) in Northeastern Brazil (Ramos et al 2010 ; Dantas-Torres et al 2021 ), differently from the Southeastern region, in which higher prevalence values (i.e., 58.7–79.2%) were reported (Miranda et al 2014 ; Spolidorio et al 2009 ).…”

Section: Discussionmentioning

confidence: 99%

Vector-borne pathogens of zoonotic concern in dogs from a Quilombola community in northeastern Brazil

et al. 2022

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Canine vector-borne pathogens (CVBPs) comprise a group of disease agents mainly transmitted by ticks, fleas, mosquitoes and sand flies. In this study, we assessed the presence of CVBPs in an Afro-descendent community (Quilombola) of northeastern, Brazil. Dog blood samples (n = 201) were collected and analyzed by rapid test for the detection of antibodies against Leishmania spp., Anaplasma spp., Ehrlichia spp. and Borrelia burgdorferi sensu lato (s.l.), and antigens of Dirofilaria immitis. In addition, polymerase chain reactions were performed for Anaplasmataceae, Babesia spp., Hepatozoon spp., Rickettsia spp. and B. burgdorferi s.l. Overall, 66.7% of the dogs scored positive to at least one pathogen at serological and/or molecular methods. Antibodies against Ehrlichia spp. were the most frequently detected (57.2%; n = 115/201), followed by Anaplasma spp. (8.5%; n = 17/201), Leishmania spp. (8.5%; n = 17/201) and B. burgdorferi s.l. (0.5%; n = 1/201). For D. immitis, 11 out of 201 (5.5%) animals scored positive. At the molecular analysis, 10.4% (n = 21/201) of the samples scored positive for Babesia spp./Hepatozoon spp., followed by Anaplasmataceae (5.0%; n = 10/201) and Rickettsia spp. (3.0%; n = 6/201). All samples were negative for B. burgdorferi s.l. Our data demonstrated the presence of CVBPs in the studied population, with a high seropositivity for Ehrlichia spp. In addition, considering the detection of zoonotic pathogens in dogs and their relationship with people from Quilombola communities, effective control strategies are advocated for minimizing the risk of infection in this socially vulnerable human population and their pets.

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“…Regarding factors associated with infection (Table 1); although, male and defined-breed dogs exhibited higher positivity, variables, such as sex and breed, revealed no statistical association with Babesia spp. infection as COSTA-JÚNIOR et al (2009), SILVA et al (2012), ARAÚJO et al (2015), and PAULINO et al (2018 reported in their studies.…”

Section: ) ---------------------------------------------------------mentioning

confidence: 91%

“…Although, no statistical difference was observed in relation to age and infection with Babesia spp., the frequency of positive dogs was higher in the group of animals<1 year of age (5.3%). Accounting for factors such as immature immune system associated with the stress of adapting to a new environment and a new diet, young and weaned dogs are actually more susceptible to disease (PAULINO et al, 2018). However, some reports in the literature described a higher prevalence in adult dogs (GUIMARÃES et al 2009;ARAÚJO et al, 2015;SILVA et al 2016), attributing senility to greater infestation and time to vector exposure, thus increasing the possibility of acquiring the infection.…”

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confidence: 99%

Molecular prevalence and factors associated with Babesia vogeli infection in dogs in the Cerrado Mato-Grossense region of Brazil

et al. 2020

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Canine babesiosis is a common haemoparasitosis in Brazil. Caused by parasites of the genus Babesia, it is transmitted by ixodid ticks and affects domestic and wild canids. The objective of this study was to verify the prevalence of Babesia species (spp.) using molecular methods in dogs living in urban and rural areas of Cuiabá, Mato Grosso State, Brazil, and to identify the main factors associated with infection. A total of 407 samples from 407 dogs were evaluated using a polymerase chain reaction (PCR) technique, among which Babesia species (spp.) was amplified in 10 (2.5%). Although, no statistical association was found among the variables studied (p>0.05), greater positivity was observed in dogs<1 year of age, male sex, those with free access to the street, and the presence of ticks. PCR samples positive for Babesia spp. were submitted to sequencing and compared in GenBank and exhibited a high degree of similarity with Babesia vogeli sequences.

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Molecular epidemiology of Babesia vogeli in dogs from the southeastern region of Rio de Janeiro, Brazil

Cited by 7 publications

References 22 publications

Occurrence of tick-borne pathogens in dogs in a coastal region of the state of Ceará, northeastern Brazil

Occurrence of tick-borne pathogens in dogs in a coastal region of the state of Ceará, northeastern Brazil

Vector-borne pathogens of zoonotic concern in dogs from a Quilombola community in northeastern Brazil

Molecular prevalence and factors associated with Babesia vogeli infection in dogs in the Cerrado Mato-Grossense region of Brazil

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