Molecular Epidemiology of Genital &lt;i&gt;Chlamydia &lt;/i&gt;&lt;i&gt;T&lt;/i&gt;&lt;i&gt;rachomatis&lt;/i&gt; Infection in Asymptomatic Adolescent-Young People

Cuffini, Cecilia; Bottiglieri, Marina; Kiguen, Ximena; Alonso, Carlos; Deimundo, Romina Valdes; Isa, Marı́a Beatrı́z; Cannistraci, Roxana; González, Silvia A.; Farinati, Alicia

doi:10.5923/j.microbiology.20120204.09

Cited by 8 publications

(13 citation statements)

References 26 publications

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“…It has been established that the prevalence of Chlamydia trachomatis infection is higher among adolescents. 1 Past history of Neisseria gonorrheae or other STIs, multiple sexual partners, husband that had other sex partners and lifetime sex partner >1 remained strongly associated risk factors for C. trachomatis infection. Several studies have previously demonstrated positive correlation between multiple sexual partners and increased risk for Chlamydia trachomatis infection.…”

Section: Discussionmentioning

confidence: 99%

“…1 It is the causative agent for several diseases including trachoma, urogenital infections, Chlamydia conjunctivitis, infant pneumonia, and lymphogranuloma venereum. 1 Infertility is a worldwide problem affecting more than 15-20% of married couples and commonly caused, in most developing countries, by tubal damage in women. 3 Pelvic infections from sexually transmitted organisms especially C. trachomatis have remained the commonest cause of tubal occlusion.…”

Section: Introductionmentioning

confidence: 99%

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Correlates of genital Chlamydial trachomatis infection in a cohort of infertile women in Ibadan, Nigeria

Ajani¹,

Oluwasola²,

Anaedobe³

et al. 2017

Int J Reprod Contracept Obstet Gynecol

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Background: Genital Chlamydial trachomatis infection, though often asymptomatic, is an established indirect causative agent of female infertility via its activities on the tubal physiology. Many risk factors are postulated for its acquisition and the main thrust of this study was to establish the organisms’ correlates among infertile women attending gynaecologic clinic in Ibadan.Methods: A systematic sampling technique was used on each selected day to recruit women who met the inclusion criteria into the study using a sampling frame of 2. Interviewer-administered questionnaires were used to obtain attributes considered as risk factors for acquiring genital Chlamydia trachomatis infection from 150 consenting infertile women between January and November 2015. These attributes included sexual history, social status, alcohol intake and past history of sexually transmitted infections (STIs). Blood samples and endocervical swabs were subsequently taken for detection of C. trachomatis infection using polymerase chain reaction (PCR). Data analysis was done using SPSS version 20.0.Results: The mean age of the respondents was 34.1±5.6 years and 7.30% were positive for C. trachomatis. Chlamydia trachomatis infection was significantly associated with past history of gonorrhoea, history of multiple sexual partners, husband that has other sexual partners and lifetime sexual partners greater than one.Conclusions: The prevalence of asymptomatic C. trachomatis among infertile women indicated the pathogen as a potential aetiologic agent of female infertility and supported the asymptomatic nature of the infection. The risk factors found to be associated with the organisms’ infection lend out further support to the sexual transmissibility of C. trachomatis.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Correlates of genital Chlamydial trachomatis infection in a cohort of infertile women in Ibadan, Nigeria

Ajani¹,

Oluwasola²,

Anaedobe³

et al. 2017

Int J Reprod Contracept Obstet Gynecol

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“…Sobrevive no interior das células humanas [2][3][4] estabelecendo uma relação de parasitismo com persistência e evasão dos mecanismos de defesa 5,6 . A espécie possui 02 biotipos: tracoma, com 13 sorotipos (A, B, Ba e C-K) e linfogranuloma venéreo (LVG), com 03 sorotipos (L1,L2 e L3) 5,6 .…”

unclassified

“…No sexo feminino a infecção inicia-se no colo do útero e uretra, causando endocer-vicite e disúria 8 e pode ascender às trompas originando consequências reversíveis e irreversíveis à saúde da mulher, tais como dor pélvica crônica (DIP), infertilidade, aumento na incidência de gravidez ectópica, associação com neoplasia intra -epitelial cervical ou carci-noma do colo do útero 8,9 , quando não diagnosticada e tratada adequadamente. Parceiros sexuais múltiplos, o desconhecimento sobre as IST, o não uso de preservativos, DST preexistentes, comportamentos de risco, uso de drogas ilícitas, álcool e fumo, condições socioculturais/econômicas desfavoráveis, são os principais fatores de risco associados à infecção por Chlamydia 3,10,11 . Outros fatores podem meramente estar relacionados ao comportamento sexual de risco dos parceiros envolvidos 8 .…”

unclassified

Prevalência e Riscos de Infecção Genital Feminina por Chlamydia Trachomatis: Revisão Sistemática

Matos

Taminato²,

Machado³

et al. 2014

Rev. bras. ciênc. Saúde

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da LILACS e 68 da SciELO. Destes, 50 relataram a prevalência, sendo a menor 0,84% e a maior 45,2%. Entre os 15 artigos brasileiros, a maior prevalência reportada foi de 33,3% e a menor 5%. Os fatores de risco/predisponentes de risco à infecção por CT mais frequentes foram a idade entre 20-25 anos, precocidade do início das relações sexuais, história de parceiros com DST, história de múltiplos parceiros sexuais, falta de adesão a métodos de proteção sexual (camisinha), nuliparidade e aspectos clínicos que não são observados pelos profissionais da saúde durante os exames de rotina. Conclusão: Prevalências entre 4 a 20% foram verificadas na maior parte dos artigos analisados e nas regiões brasileiras os índices geralmente foram superiores a 5%. Múltiplas condições podem estar envolvidas na infecção por CT, sendo necessária a realização de mais estudos em grupos populacionais diversificados para melhor caracterização dos fatores de risco. DESCRITORESChlamydia Trachomatis. Fatores de Risco. Prevalência. ABSTRACT Objective:To verify the risk factors related to the prevalence of Chlamydia trachomatis (CT) in sexually active women. Material and Methods: A systematic review through electronic searches was performed in the databases: Cochrane Library, EMBASE, LILACS, PUBMED, and SciELO. Controlled and uncontrolled descriptors were used, such as Chlamydia trachomatis, prevalence, risk factors, according to the PICO and COCHRANE strategies. Results: We selected descriptive articles on risk behaviors among adolescents and young people, in Portuguese, English and Spanish from PUBMED (n=220), MEDLINE (n=109), LILACS (n=138) and SciELO (n=68). Of these, 50 articles reported prevalence data ranging from 0.84% to 45.2%. Among the 15 Brazilian articles, the prevalence ranged from 5% to 33.3%. The most frequent risk factors/ predisposing risk factors to infection by CT were: aged 20-25 years, beginning of sexual intercourse, partner with STD history, history of multiple sexual partners, lack of adherence to sexual protection methods (condom), nulliparity and clinical aspects that are not observed by health professionals during routine examinations. Conclusion: Prevalence ranging between 4% and 20% was observed in most of the analyzed articles, and in Brazilian regions it was generally higher than 5%. Multiple conditions can be involved in the CT infection, requiring further studies in different populations to better characterize the risk factors. DESCRIPTORS

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“…Cytological analysis for the detection of Chlamydia trachomatis, available since 1907, was the first method used in cell samples and inclusion conjunctivitis secretions in infants (1,6) . Other methods, such as complement fixation test, cell culture, and hybrid capture, were subsequently developed, and the last two show high sensitivity and specificity (16)(17)(18)(19) . Nowadays, modern laboratory tests are available, using immunological and molecular techniques based on nucleic acid amplification, such as polymerase chain reaction (PCR) (16)(17)(18)(19) .…”

Section: Introductionmentioning

confidence: 99%

Detection of chlamydia trachomatis by immunological methods in adult and adolescent female population in Cuiabá, Mato Grosso

Matos¹,

Machado²,

Zavala³

et al. 2015

J Bras Doenças Sex Transm

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ARTICLE INTRODUCTIONThe WHO estimates that there are 105.7 million new cases of Chlamydia worldwide, with 3 to 4 million of these only in the United States of America (USA), with over 1.4 million cases reported in 2011 (1)(2)(3)(4)(5) , 5 million in Eastern Europe, and 34 million in subSaharan Africa and southeast Asia (5)(6)(7)(8)(9) . Worldwide, it occurs more frequently in sexually active young adults, generally aged younger than 20 years, and it is nearly three times higher in the 14-24 years age group (5,7,9,10) . It currently represents the leading cause of female infertility, but the most common infections are urethritis and cervicitis, which, if untreated, can lead to serious consequences in the reproductive tract such as ectopic pregnancy and infertility (6,(8)(9)(10) . About 50% of infected men and 70 to 75% of infected women are asymptomatic. The infection is transmitted during sexual contact and to the newborn at birth and may cause neonatal conjunctivitis or pneumonia (5,6,(8)(9)(10) . Over 100 million individuals of both sexes worldwide are infected with Chlamydia at some point in their lives (6,9,10) . Among male subjects, the prevalence is comparable with that of risk populations, ranging from 15 to 20%, while in the asymptomatic population, it is between 3 and 7%. In female subjects, the infection rates of asymptomatic populations are between 3 and 10%, while in high-risk populations they are above 20% (1)

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Molecular Epidemiology of Genital <i>Chlamydia </i><i>T</i><i>rachomatis</i> Infection in Asymptomatic Adolescent-Young People

Cited by 8 publications

References 26 publications

Correlates of genital Chlamydial trachomatis infection in a cohort of infertile women in Ibadan, Nigeria

Correlates of genital Chlamydial trachomatis infection in a cohort of infertile women in Ibadan, Nigeria

Prevalência e Riscos de Infecção Genital Feminina por Chlamydia Trachomatis: Revisão Sistemática

Detection of chlamydia trachomatis by immunological methods in adult and adolescent female population in Cuiabá, Mato Grosso

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