Molecular Epidemiology of &lt;i&gt;Trichophyton tonsurans&lt;/i&gt;, the Causative Dermatophyte of the Tinea Gladiatorum Epidemic in Japan between 2011 and 2015

Sakata, Yuichi; Ushigami, Tsuyoshi; Anzawa, Kazushi; Mochizuki, Takashi

doi:10.7883/yoken.jjid.2017.449

Cited by 11 publications

(19 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…They were obtained from individuals that participated in sports including judo (n = 67), wrestling (n = 14), sumo (n = 11), and others (n = 2; 1 martial arts, 1 baseball). Since we maintain a culture collection of 711 T. tonsurans strains previously isolated (2001 to June 2006: 237 strains; July 2006 to 2010: 264 strains; 2011 to 2015: 210 strains), 10–13 a screening test for TBF resistance was performed among strains newly isolated in the present study and the maintained culture collection. Genotypes of all strains in the culture collection had been determined 10–13 .…”

Section: Methodsmentioning

confidence: 99%

“…We conducted screening for T. tonsurans infection among groups engaged in contact sports around the year 2000 to inform prevention of an epidemic 10–13 . We reported the trend of infection by the pathogen, and examined molecular types of isolates using restriction enzyme fragment length polymorphism (RFLP) in the non‐transcription spacer (NTS) region of ribosomal RNA gene in years 2000 and 2015 10–13 . In the present study, we discuss the 20‐year trend of T. tonsurans infection in Japan.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Genotyping ofTrichophyton tonsuransstrains isolated between 2016 and 2020, and terbinafine susceptibility of the species in Japan

Futatsuya

Taga

Sakata

et al. 2022

The Journal of Dermatology

Self Cite

View full text Add to dashboard Cite

Trichophyton tonsurans, an anthropophilic dermatophyte, causes dermatophytosis such as tinea corporis showing erythema with/ without central healing tendency, tinea capitis showing black dots, scaliness, hair loss and purulent follicular inversion known as kerion celsi, and tinea unguium. Large scale studies have reported that cultural practices influence the transmission of particular mycoses, with more than 95% of tinea capitis infections caused by T. tonsurans. 1,2 In Japan, an epidemic has been ongoing among contact sports athletes since the early 2000s. 3,4 Mycological surveys conducted by the Japanese Society for Medical Mycology revealed a nationwide spread of T. tonsurans infection among school judo, wrestling, and sumo teams. [5][6][7][8] Oral terbinafine (TBF) and itraconazole (ITZ) are recommended to treat this infection. 9 However, there are patients who remain uncured or are re-infected after treatment; therefore, the possibility of the presence of drug-resistant isolates is of great dermatological interest.We conducted screening for T. tonsurans infection among groups engaged in contact sports around the year 2000 to inform prevention of an epidemic. [10][11][12][13] We reported the trend of infection by the pathogen, and examined molecular types of isolates using restriction enzyme fragment length polymorphism (RFLP) in the nontranscription spacer (NTS) region of ribosomal RNA gene in years 2000 and 2015. [10][11][12][13] In the present study, we discuss the 20-year trend of T. tonsurans infection in Japan. During the past two decades,

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Genotyping ofTrichophyton tonsuransstrains isolated between 2016 and 2020, and terbinafine susceptibility of the species in Japan

Futatsuya

Taga

Sakata

et al. 2022

The Journal of Dermatology

Self Cite

View full text Add to dashboard Cite

show abstract

“…9 During last few decades, many researchers have tried to design new molecular methods for fast identification of dermatophyte fungi at the species level in clinical specimens and cultures. [10][11] Alternative molecular methods to the identification of dermatophyte fungi have been used through techniques such as arbitrarily primed PCR, 12 random amplified polymorphic DNA analysis, 13,14 and restriction analysis of mitochondrial DNA 15 and recombinant DNA (rDNA), 16,17 which are generally adequate for various species.…”

Section: Introductionmentioning

confidence: 99%

Dermatophyte Monitoring in an Iranian Training Dermatology Hospital

et al. 2022

View full text Add to dashboard Cite

Introduction: The most common cutaneous fungal infections are caused by dermatophyte fungi such as Microsporum, Trichophyton, and Epidermophyton. In this study, the epidemiologic trends and the predominant organisms causing dermatophytosis in Urmia, Northwest Iran, were identified.Aims and objectives: To get better perception of dermatophyte distribution in Northwest Iran, the authors studied the identification of isolated dermatophytes from human specimens by using a fast and cheap molecular method: PCR-based restriction fragment length polymorphism (PCR-RFLP). The authors also aimed to use this method in for rapid and reliable identification of medically important and common dermatophytes at the level of species. Methods: The study samples were collected from clinically suspected cutaneous lesions. All the specimens were transported to Medical Mycology Center, Urmia Medical Sciences University (UMS), Iran. First of all, a conventional diagnosis was carried out, which included microscopic examination and culture of sabouraud dextrose agar medium with antibiotics: chloramphenicol and cycloheximide. All the dermatophyte isolates were then identified at the level of species by the molecular method of PCR-RFLP. Results: From the tested 357 clinical specimens, 30 dermatophytic isolates were identified. The percentage rate of dermatophyte species were Trichophyton mentagrophytes (36%), Microsporum canis (32%), Microsporum gypseum (16%), Trichophyton rubrum (4%), and Epidermophyton floccosum (12%). Conclusion: By using of PCR-RFLP, a fast and reliable identification of these species is possible. This molecular method provided an opportunity for dermatophyte identification at the species level.

show abstract

“…Infections with the anthropophilic dermatophyte Trichophyton (T) tonsurans have been described worldwide, mainly in the context of martial arts and other contact sports 1 which require proximity between the athletes. Here, the pathogen regularly triggers local and supra‐regional outbreaks of tinea corporis in sports clubs but also during competitions, which is why the disease caused by this dermatophyte is also called ‘Tinea gladiatorum’ 2,3 . Originally, T tonsurans was native to South East Asia and Australia.…”

Section: Introductionmentioning

confidence: 99%

“…Here, the pathogen regularly triggers local and supra-regional outbreaks of tinea corporis in sports clubs but also during competitions, which is why the disease caused by this dermatophyte is also called 'Tinea gladiatorum'. 2,3 Originally, T tonsurans was native to South East Asia and Australia. In the colonial period, it expanded to Central and South America, and from there, through both migration and international combat sports competitions, to Europe and the United States.…”

Section: Introductionmentioning

confidence: 99%

Tinea capitis et barbae caused by Trichophyton tonsurans: A retrospective cohort study of an infection chain after shavings in barber shops

Müller

Kappa-Markovi

Hyun

et al. 2020

Mycoses

View full text Add to dashboard Cite

Background Tinea capitis is a highly contagious infectious disease caused by dermatophytes. In Central Europe, it is mainly caused by zoophilic dermatophytes, as, for example Microsporum (M) canis or Trichophyton (T) mentagrophytes and increasingly by anthropophilic fungi. T tonsurans was commonly related to the Tinea gladiatorum, where transmission occurred between infected persons or via contaminated floors. Objective Reporting the transmission of this highly contagious dermatophyte for the first time via beard shaving and hairdressing in barber shops in Germany. Patients and methods 18 young male patients developed tinea capitis and/or barbae shortly after shavings of the beard and/or hair in a barber shop. Native, cultural and molecular diagnostics as well as tissue biopsies and resistance tests were performed of skin and hair samples. Results In all samples, T tonsurans could be identified. The medical history and the clinical picture suggest a transmission through contaminated hairdressing tools. The patients were treated with terbinafine or itraconazole in combination with or exclusively with topical antimycotics. Conclusion The transmission and a resulting increase in the incidence of infections with T tonsurans may be due to shavings with direct skin contact of insufficiently disinfected hairdressing tools. This path of infection has already been observed in Africa and is now being described for the first time in Germany. Knowledge of the pathogen and its transmission ways are essential to interrupt the chain of infection.

show abstract

Molecular Epidemiology of <i>Trichophyton tonsurans</i>, the Causative Dermatophyte of the Tinea Gladiatorum Epidemic in Japan between 2011 and 2015

Cited by 11 publications

References 21 publications

Genotyping ofTrichophyton tonsuransstrains isolated between 2016 and 2020, and terbinafine susceptibility of the species in Japan

Genotyping ofTrichophyton tonsuransstrains isolated between 2016 and 2020, and terbinafine susceptibility of the species in Japan

Dermatophyte Monitoring in an Iranian Training Dermatology Hospital

Tinea capitis et barbae caused by Trichophyton tonsurans: A retrospective cohort study of an infection chain after shavings in barber shops

Contact Info

Product

Resources

About