Molecular epidemiology of Mycobacterium bovis: Usefulness in international trade

Milián-Suazo, Feliciano; Harris, Beth; Dı́az, Carlos; Torres, Cecilia Romero; Stuber, Tod; Ojeda, Genoveva Álvarez; Loredo, Alberto Morales; Soria, Martina Perez; Payeur, Janet B.

doi:10.1016/j.prevetmed.2008.04.004

Cited by 27 publications

(24 citation statements)

References 21 publications

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“…By 1998, bTB was identified in both cattle and deer . Genetic analysis of M. bovis strains suggests interspecific transmission between deer and cattle (Millian-Suazo et al 2008). A similar situation was documented in Minnesota in 2005 (Portacci et al 2008).…”

Section: Introductionsupporting

confidence: 60%

Characteristics of white-tailed deer visits to cattle farms: implications for disease transmission at the wildlife–livestock interface

et al. 2013

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Bovine tuberculosis (bTB) is endemic in freeranging white-tailed deer (Odocoileus virginianus) in MI, USA. Currently, the rates of farm visitation by deer and couse of forage resources by cattle and deer are poorly understood. To evaluate the extent deer and livestock may share forage resources, we investigated farm, yard, and cattle-use area visitation by white-tailed deer and compared visitation with common livestock management practices. We fitted 25 female white-tailed deer near the bTB-infected zone in Michigan's Lower Peninsula with global positioning system collars. Livestock management practices associated with farm visitation included presence of confined feeding pastures, number of cattle water sources, and the number of cattle pastures. Fewer farm visits occurred at night than during the day. A higher proportion of nighttime visits occurred between midnight and sunrise. Visitation to yards and cattle-use areas were similar: a higher proportion of visits occurred at night, and a higher proportion of nighttime visits occurred between midnight and sunrise. Multiple visits during the same day were common. Visitation increased through spring and peaked during the fawning season. Results suggest that mitigation and control efforts to guard against potential transmission of bTB should include the season and time of day during which deer visitation occurs. Furthermore, specific livestock management practices may contribute to farm visitation by deer. Deer visiting multiple farms may contribute to local area spread of bTB.Focusing risk mitigation efforts on individual deer that are most likely to visit farms may reduce potential bTB transmission.

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Section: Introductionsupporting

confidence: 60%

Characteristics of white-tailed deer visits to cattle farms: implications for disease transmission at the wildlife–livestock interface

et al. 2013

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“…Although the number of strains sampled in each of these countries was small, the high frequency of Af1 in the four west-central African countries supports our conclusion that the Af1 clonal complex is not uniformly distributed throughout Africa but is dominant in sub-Saharan west-central Africa. Previously published large-scale spoligotype population surveys of M. bovis strains from Europe (France, Spain, United Kingdom, Italy, Germany, Belgium, Czech Republic, and Portugal) (2,5,6,19,20,31,33,39,55,59,61,70), the Middle East (Iran) (63), and South and Central America (14,45,71) do not show a high frequency of strains with spacer 30 missing, suggesting that if Af1 strains are present, they are not at the high frequency seen in west-central Africa and supporting our suggestion of geographical localization of the Af1 clonal complex to this region of Africa.…”

Section: Discussionmentioning

confidence: 99%

“…Identification of these clonal complexes will assist the epidemiological analysis of the international movement of M. bovis strains, not only in cattle, but also in humans (45). A strain of M. bovis isolated in 2005 from a human at the Midlands Regional Centre for Mycobacteriology, Birmingham, United Kingdom, had the commonest genotype seen in our Nigerian sample (SB0944; 5 5 3 4* 3 3.1) (21).…”

Section: Discussionmentioning

confidence: 99%

African 1, an Epidemiologically Important Clonal Complex of Mycobacterium bovis Dominant in Mali, Nigeria, Cameroon, and Chad

et al. 2009

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We have identified a clonal complex of Mycobacterium bovis present at high frequency in cattle in population samples from several sub-Saharan west-central African countries. This closely related group of bacteria is defined by a specific chromosomal deletion (RDAf1) and can be identified by the absence of spacer 30 in the standard spoligotype typing scheme. We have named this group of strains the African 1 (Af1) clonal complex and have defined the spoligotype signature of this clonal complex as being the same as the M. bovis BCG vaccine strain but with the deletion of spacer 30. Strains of the Af1 clonal complex were found at high frequency in population samples of M. bovis from cattle in Mali, Cameroon, Nigeria, and Chad, and using a combination of variable-number tandem repeat typing and spoligotyping, we show that the population of M. bovis in each of these countries is distinct, suggesting that the recent mixing of strains between countries is not common in this area of Africa. Strains with the Af1-specific deletion (RDAf1) were not identified in M. bovis isolates from Algeria, Burundi, Ethiopia, Madagascar, Mozambique, South Africa, Tanzania, and Uganda. Furthermore, the spoligotype signature of the Af1 clonal complex has not been identified in population samples of bovine tuberculosis from Europe, Iran, and South America. These observations suggest that the Af1 clonal complex is geographically localized, albeit to several African countries, and we suggest that the dominance of the clonal complex in this region is the result of an original introduction into cows naïve to bovine tuberculosis.

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“…The exception is South Africa where an extensive test-and-slaughter has reduced the disease in cattle to minimal levels (Michel et al, 2008). In North America bovine TB is endemic in Mexican cattle but has been largely eliminated from cattle in the USA and Canada (Milian-Suazo et al, 2008;Wobeser, 2009). However, in the USA a persistent problem has been reported in white-tailed deer in Michigan, as well as small breakdowns in Minnesota and Molokai Island, Hawaii (associated with feral swine) (Bany and Freier, 2000).…”

Section: Introductionmentioning

confidence: 99%

“…However, in the USA a persistent problem has been reported in white-tailed deer in Michigan, as well as small breakdowns in Minnesota and Molokai Island, Hawaii (associated with feral swine) (Bany and Freier, 2000). The USA also suffers from the occasional import of bovine TB in Mexican cattle (Milian-Suazo et al, 2008;Rodwell et al, 2010). In Canada there are two areas where wildlife populations are still infected with bovine TB; free-ranging populations of wood bison in and around Wood Buffalo National Park, which straddles the provinces of Alberta and the Northwest Territories, and deer and elk (wapiti) in Riding Mountain National Park, Manitoba (Wobeser, 2009).…”

Section: Introductionmentioning

confidence: 99%

European 1: A globally important clonal complex of Mycobacterium bovis

Smith

Berg

Dale

et al. 2011

Infection, Genetics and Evolution

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104

103

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We have identified a globally important clonal complex of M. bovis by deletion analysis of over one thousand strains from over 30 countries. We initially show that over 99% of the strains of Mycobacterium bovis, the cause of bovine tuberculosis, isolated from cattle in the Republic of Ireland and the UK are closely related and are members of a single clonal complex marked by the deletion of chromosomal region RDEu,1 and we named this clonal complex European 1 (Eu1). Eu1 strains were present at less than

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Molecular epidemiology of Mycobacterium bovis: Usefulness in international trade

Cited by 27 publications

References 21 publications

Characteristics of white-tailed deer visits to cattle farms: implications for disease transmission at the wildlife–livestock interface

Characteristics of white-tailed deer visits to cattle farms: implications for disease transmission at the wildlife–livestock interface

African 1, an Epidemiologically Important Clonal Complex of Mycobacterium bovis Dominant in Mali, Nigeria, Cameroon, and Chad

European 1: A globally important clonal complex of Mycobacterium bovis

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