Molecular evolution of viruses; ‘trees’, ‘clocks’ and ‘modules’

Gibbs, Adrian

doi:10.1242/jcs.1987.supplement_7.22

Cited by 53 publications

(26 citation statements)

References 80 publications

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“…Among these differences are the location of the coat protein cistron at the 3' end of the genome, the requirement of three proteolytic activities for polyprotein processing, and the sequence similarities between some non-structural and structural potyviral proteins and the equivalent proteins of some otherwise unrelated viruses (see below). These findings strongly support the idea that recombination of distinct gene sets occurred during virus evolution (the term 'modular evolution' refers to the mixing and joining of such modules; Zimmern, 1987;Gibbs, 1987), and indicate that these events can follow complex pathways (Goldbach, 1987).…”

Section: Genome Structure and Organizationsupporting

confidence: 75%

Highlights and prospects of potyvirus molecular biology

Riechmann

Laı́n

Garcı́a

1992

Journal of General Virology

576

355

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Section: Genome Structure and Organizationsupporting

confidence: 75%

Highlights and prospects of potyvirus molecular biology

Riechmann

Laı́n

Garcı́a

1992

Journal of General Virology

576

355

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“…Double infection of a bacterial host by different phages and homologue recombination or incorrect excision and packaging of the phage DNA may lead to the transfer of DNA fragments of different origin. This is discussed as a fundamental idea for a model of modular evolution for viruses (Kim & Davidson 1974, Mise 1976, Schwarz et al 1983, Gibbs 1987, Jarvis 1995.…”

Section: Discussionmentioning

confidence: 99%

“…In contrast to the species concept of Ackermann et al (1992), 5 phages showed DNA homologies with 2 virus families. This may be due to DNA fragments, which can be transferred to different phage species via double infection with 2 phages and homologue recombination (Botstein 1980, Gibbs 1987. Double infection of a bacterial host by different phages and homologue recombination or incorrect excision and packaging of the phage DNA may lead to the transfer of DNA fragments of different origin.…”

mentioning

confidence: 99%

Pseudoalteromonas spp. phages, a significant group of marine bacteriophages in the North Sea

Wichels¹,

Gerdts²,

Schütt³

2002

Aquat. Microb. Ecol.

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The occurrence and distribution of specific bacteriophages of marine Pseudoalteromonas spp. in the North Sea (North Sea phages) and their genetic relationship to several previously isolated marine phage species from waters of the Helgoland Roads (German Bight, Helgoland phages) were investigated. During 3 cruises from the Elbe estuary to western Norwegian waters, phages were concentrated by ultrafiltration. Detection and isolation of North Sea phages were performed by plaque assay, with 70 host bacteria of the genus Pseudoalteromonas. The genetic relationship between North Sea phages from different stations and Helgoland phages, formerly described as Pseudoalteromonas spp. phages, was assessed by DNA-DNA hybridization. DNA probes were prepared using whole phage DNA derived from 13 Helgoland phages. This approach provides the first information on the distribution of specific Pseudoalteromonas spp. phage-host systems (PHS) in the North Sea. The occurrence of Pseudoalteromonas spp. phages, which are specific for the tested Pseudoalteromonas spp. host bacteria, was restricted to a narrow geographical region of the German Bight between 53°30' and 57°00' N latitude. Most of the previously isolated Helgoland phages were highly host specific (54%), whereas this was true for only some of the 39 North Sea phages (16%). The most common Pseudoalteromonas spp. phage species found in the North Sea belong to the virus family Siphoviridae (species H103/1). Several phage strains within this phage species displayed different host sensitivity patterns.KEY WORDS: Marine phages · Pseudoalteromonas · Phage DNA probes · North Sea Resale or republication not permitted without written consent of the publisherAquat Microb Ecol 27: [233][234][235][236][237][238][239] 2002 species infecting Pseudoalteromonas spp. in the North Sea. Our previous work on DNA homologies among 22 different marine phages, as determined by DNA-DNA hybridization, showed that the whole DNA of each phage was specific for only 1 phage species (Wichels et al. 1998). These results suggest that phage DNA can be used as specific DNA probes in order to identify single phage species. Data elucidating the genetic relatedness and host range of Helgoland phages and North Sea phages are presented. MATERIALS AND METHODSWater samples were collected during 3 cruises to the North Sea. Samples were tested for plaque formation on 70 bacterial isolates belonging to the genus Pseudoalteromonas. After isolation and purification of the new Pseudoalteromonas spp. phages, they were characterized by DNA hybridization and host range cross-reaction test, in order to assign them to a virus family and a phage species.Bacterial strains, phages and media. Seventy marine bacterial host strains and 13 lytic phages were provided by Moebus (1992a,b). They were isolated from water samples collected at Helgoland Roads (HR; 54°09' N, 7°52' E; Fig. 1), which is located approximately 55 km offshore in the German Bight. In order to characterize the 70 host bacteria, colony hybridization was p...

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“…Most types of DNA and RNA viruses are prone to high rates of recombination, except for viruses with negative strand RNA genomes (Chare et al, 2003). Major innovations in virus evolution are often the result of extensive exchange of a common pool of genetic modules (Botstein, 1980;Gibbs, 1987;Hendrix et al, 1999;Pedulla et al, 2003). Viruses also provide a substantial conduit for HGT between other organisms such as bacteria (Breitbart and Rohwer, 2005).…”

Section: Type Of Organismmentioning

confidence: 99%

Risks from GMOs due to Horizontal Gene Transfer

Keese¹

2008

Environ. Biosafety Res.

135

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Horizontal gene transfer (HGT) is the stable transfer of genetic material from one organism to another without reproduction or human intervention. Transfer occurs by the passage of donor genetic material across cellular boundaries, followed by heritable incorporation to the genome of the recipient organism. In addition to conjugation, transformation and transduction, other diverse mechanisms of DNA and RNA uptake occur in nature. The genome of almost every organism reveals the footprint of many ancient HGT events. Most commonly, HGT involves the transmission of genes on viruses or mobile genetic elements. HGT first became an issue of public concern in the 1970s through the natural spread of antibiotic resistance genes amongst pathogenic bacteria, and more recently with commercial production of genetically modified (GM) crops. However, the frequency of HGT from plants to other eukaryotes or prokaryotes is extremely low. The frequency of HGT to viruses is potentially greater, but is restricted by stringent selection pressures. In most cases the occurrence of HGT from GM crops to other organisms is expected to be lower than background rates. Therefore, HGT from GM plants poses negligible risks to human health or the environment.

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Molecular evolution of viruses; ‘trees’, ‘clocks’ and ‘modules’

Cited by 53 publications

References 80 publications

Highlights and prospects of potyvirus molecular biology

Highlights and prospects of potyvirus molecular biology

Pseudoalteromonas spp. phages, a significant group of marine bacteriophages in the North Sea

Risks from GMOs due to Horizontal Gene Transfer

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