Molecular fluorescent sensors for in vivo imaging

Adair, Liam D.; New, Elizabeth J.

doi:10.1016/j.copbio.2023.102973

Cited by 7 publications

(3 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Small molecular fluorophores have been extensively used in cell biology experiments, diagnostics, and clinical applications. 8,33–35 Recently, researchers have skillfully designed small molecular probes tailored to specific organelles. 33–36 The primary strategy for precise organelle targeting involves the conjugation of a functional group with the fluorophore to guide it to the intended organelles.…”

Section: Introductionmentioning

confidence: 99%

“…8,33–35 Recently, researchers have skillfully designed small molecular probes tailored to specific organelles. 33–36 The primary strategy for precise organelle targeting involves the conjugation of a functional group with the fluorophore to guide it to the intended organelles. 8,37,38 This approach is favoured for its straightforwardness and effectiveness in bio-sensing and imaging technology.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Chronological development of functional fluorophores for bio-imaging

Munan,

Chang,

Samanta

2024

Chem. Commun.

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Chronological development of functional fluorophores for bio-imaging

Munan,

Chang,

Samanta

2024

Chem. Commun.

View full text Add to dashboard Cite

show abstract

“…This species exists in equilibrium with quinoidal base, hemiketal, and cis- and trans- chalcones, whereby the equilibria can be perturbed by light, temperature, and pH due to the complex solution-state speciation profile (Scheme ). The tunability of the substituent groups and their conjugated structure make the molecules ideal candidates for the development of novel and smart chromophores and fluorophores. − …”

Section: Introductionmentioning

confidence: 99%

Flavylium-Containing Stimuli-Responsive RAFT Polymers: Synthesis and Enhanced Stability

Liu,

McDonald,

Thang

et al. 2024

Macromolecules

View full text Add to dashboard Cite

Flavyliums are abundant naturally occurring, stimuli-responsive cationic chromophores found in anthocyanins that constitute the majority of red and blue pigments found in flora. While synthetic molecular derivatives have been devised to finetune these characteristics, the development of polymeric materials in this regard remains scarce. To address this, a flavylium-based methacrylamide derivative (FlavM-A1) was successfully synthesized, but its radical polymerization proved to be ineffective. To overcome this constraint, a convergent synthetic route for a series of flavylium-containing polymers was developed, employing reversible addition−fragmentation chain transfer (RAFT) polymerization followed by postmodification to install the flavylium chromophore. The flavylium-containing polymers described in this work exhibit improved hydrolytic stability in their flavylium moieties compared to the small-molecule FlavM-A1 while both possess interesting stimuli responsiveness and surfactant-like properties.

show abstract