Molecular genealogy of Tusi Lu’s family reveals their paternal relationship with Jochi, Genghis Khan’s eldest son

Wen, Shaoqing; Yao, Hongbing; Du, Pengfei; Wei, Lan‐Hai; Tong, Xin-Zhu; Wang, Ling-Xiang; Wang, Chuan‐Chao; Zhou, Boyan; Shi, Meisen; Zhabagin, Maxat; Wang, Jiucun; Xu, Dan; Li, Jin; Li, Hui

doi:10.1038/s10038-019-0618-0

Cited by 12 publications

(6 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The derived Eastern Eurasian ancestry (ANA) from a gene pool was similar to contemporary Tungusic speakers from Amur River Basin, suggesting a genetic connection among the speakers of languages belonging to the Altaic macrofamily (Turkic, Mongolic, and Tungusic language families) (Yunusbayev et al, 2015;Pugach et al, 2016;Chen et al, 2021;Zhang et al, 2021). The genetic connection of Mongolic and Tungusic populations was also shown in a similar pattern of the paternal Y chromosomes (Huang et al, 2018a;Huang et al, 2018b;Wen et al, 2019;Wei et al, 2018a;Yan et al, 2015;Wei et al, 2018b). Trans-Eurasian language origin hypothesis asserted that the language subfamily of Mongolic, Tungusic, Turkic, and Japonic-Korean originated from Neolithic Hongshan culture in West Liao River Basin; the Hongshan farmers in West Liao River Basin migrated westward to the Mongolia Plateau and gradually developed into nomadic style, leading to the separation of Proto-Turkic and Proto-Mongolic-Tungusic languages.…”

Section: Discussionmentioning

confidence: 69%

Genomic Insights Into the Genetic Structure and Natural Selection of Mongolians

Yang

Sarengaowa

et al. 2021

Front. Genet.

Self Cite

View full text Add to dashboard Cite

Mongolians dwell at the Eastern Eurasian Steppe, where is the agriculture and pasture interlaced area, practice pastoral subsistence strategies for generations, and have their own complex genetic formation history. There is evidence that the eastward expansion of Western Steppe herders transformed the lifestyle of post-Bronze Age Mongolia Plateau populations and brought gene flow into the gene pool of Eastern Eurasians. Here, we reported genome-wide data for 42 individuals from the Inner Mongolia Autonomous Region of North China. We observed that our studied Mongolians were structured into three distinct genetic clusters possessing different genetic affinity with previous studied Inner Mongolians and Mongols and various Eastern and Western Eurasian ancestries: two subgroups harbored dominant Eastern Eurasian ancestry from Neolithic millet farmers of Yellow River Basin; another subgroup derived Eastern Eurasian ancestry primarily from Neolithic hunter-gatherers of North Asia. Besides, three-way/four-way qpAdm admixture models revealed that both north and southern Western Eurasian ancestry related to the Western Steppe herders and Iranian farmers contributed to the genetic materials into modern Mongolians. ALDER-based admixture coefficient and haplotype-based GLOBETROTTER demonstrated that the former western ancestry detected in modern Mongolian could be recently traced back to a historic period in accordance with the historical record about the westward expansion of the Mongol empire. Furthermore, the natural selection analysis of Mongolians showed that the Major Histocompatibility Complex (MHC) region underwent significantly positive selective sweeps. The functional genes, alcohol dehydrogenase (ADH) and lactase persistence (LCT), were not identified, while the higher/lower frequencies of derived mutations were strongly correlated with the genetic affinity to East Asian/Western Eurasian populations. Our attested complex population movement and admixture in the agriculture and pasture interlaced area played an important role in the formation of modern Mongolians.

show abstract

Section: Discussionmentioning

confidence: 69%

Genomic Insights Into the Genetic Structure and Natural Selection of Mongolians

Yang

Sarengaowa

et al. 2021

Front. Genet.

Self Cite

View full text Add to dashboard Cite

show abstract

“…3 ). This branch, however, includes the genus Tore from Kazakhstan [ 34 ] and the genus Tusi Lu from China [ 35 ], both of which claim to be descendants of Genghis Khan. The first descend from Genghis Khan’s first son, Jochi, and the second from Khulgen’s sixth son.…”

Section: Resultsmentioning

confidence: 99%

“…Unfortunately, samples with known affiliations across 20 tribes are limited on the 17 Y-STR sites. The total sample includes 3036 Kazakh samples studied on 17 Y-STRs from previous studies [ 17 , 19 , 20 , 22 , 23 , 32 , 35 , 38 , 44 ]. The pairwise genetic distance (RST) between the populations was calculated and presented in Additional file 7 .…”

Section: Resultsmentioning

confidence: 99%

Genetic polymorphism of Y-chromosome in Kazakh populations from Southern Kazakhstan

Ashirbekov,

Seidualy,

Abaildayev

et al. 2023

BMC Genomics

Self Cite

View full text Add to dashboard Cite

Background The Kazakhs are one of the biggest Turkic-speaking ethnic groups, controlling vast swaths of land from the Altai to the Caspian Sea. In terms of area, Kazakhstan is ranked ninth in the world. Northern, Eastern, and Western Kazakhstan have already been studied in relation to genetic polymorphism 27 Y-STR. However, current information on the genetic polymorphism of the Y-chromosome of Southern Kazakhstan is limited only by 17 Y-STR and no geographical study of other regions has been studied at this variation. Results The Kazakhstan Y-chromosome Haplotype Reference Database was expanded with 468 Kazakh males from the Zhambyl and Turkestan regions of South Kazakhstan by having their 27 Y-STR loci and 23 Y-SNP markers analyzed. Discrimination capacity (DC = 91.23%), haplotype match probability (HPM = 0.0029) and haplotype diversity (HD = 0.9992) are defined. Most of this Y-chromosome variability is attributed to haplogroups C2a1a1b1-F1756 (2.1%), C2a1a2-M48 (7.3%), C2a1a3-F1918 (33.3%) and C2b1a1a1a-M407 (6%). Median-joining network analysis was applied to understand the relationship between the haplotypes of the three regions. In three genetic layer can be described the position of the populations of the Southern region of Kazakhstan—the geographic Kazakh populations of Kazakhstan, the Kazakh tribal groups, and the people of bordering Asia. Conclusion The Kazakhstan Y-chromosome Haplotype Reference Database was formed for 27 Y-STR loci with a total sample of 1796 samples of Kazakhs from 16 regions of Kazakhstan. The variability of the Y-chromosome of the Kazakhs in a geographical context can be divided into four main clusters—south, north, east, west. At the same time, in the genetic space of tribal groups, the population of southern Kazakhs clusters with tribes from the same region, and genetic proximity is determined with the populations of the Hazaras of Afghanistan and the Mongols of China.

show abstract

“…In contrast, pre-F2h is prevalent in considerable frequency in Southeast Asian populations such as in Taiwan and Thailand (Kutanan et al, 2017). The two male individuals (M311 and M312) were assigned to Y chromosome haplogroup N1b2*, which is a widespread lineage in modern Northeastern Asians such as Sino-Tibetan speaking populations (Wen et al, 2019). In short, from uniparental genetic analyses, we found that three of four individuals (M310, M311, and M312) from the Pingliangtai site were potentially maternally related and the two male individuals (M311 and M312) were probably paternally related.…”

Section: Ancient Dna Authentication and Uniparental Genetic Analysesmentioning

confidence: 98%

Ancient genome analyses shed light on kinship organization and mating practice of Late Neolithic society in China

et al. 2021

View full text Add to dashboard Cite

Anthropology began in the late nineteenth century with an emphasis on kinship as a key factor in human evolution. From the 1960s, archaeologists attempted increasingly sophisticated ways of reconstructing prehistoric kinship but ancient DNA analysis has transformed the field, making it possible, to directly examine kin relations from human skeletal remains. Here, we retrieved genomic data from four Late Neolithic individuals in central China associated with the Late Neolithic Longshan culture. We provide direct evidence of consanguineous mating in ancient China, revealing inbreeding among the Longshan populations. By combining ancient genomic data with anthropological and archaeological evidence, we further show that Longshan society household was built based on the extended beyond the nuclear family, coinciding with intensified social complexity during the Longshan period, perhaps showing the transformation of large communities through a new role of genetic kinship-based extended family units.

show abstract

Molecular genealogy of Tusi Lu’s family reveals their paternal relationship with Jochi, Genghis Khan’s eldest son

Cited by 12 publications

References 21 publications

Genomic Insights Into the Genetic Structure and Natural Selection of Mongolians

Genomic Insights Into the Genetic Structure and Natural Selection of Mongolians

Genetic polymorphism of Y-chromosome in Kazakh populations from Southern Kazakhstan

Ancient genome analyses shed light on kinship organization and mating practice of Late Neolithic society in China

Contact Info

Product

Resources

About