Encyclopedia of Life Sciences 2014
DOI: 10.1002/9780470015902.a0025222
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Molecular Genetics of Oral Cancer

Abstract: Oral squamous cell carcinoma (OSCC) is the most common epithelial malignancy in the oral cavity and constitutes more than 90% of oral malignancies. OSCC is a complex malignancy where environmental factors, viral infections and genetic alterations most likely interact, and thus give rise to the malignant condition. Epidemiological investigations have shown that heavy tobacco smoking, high alcohol consumption and human papilloma virus infection are the major risk factors for OSCC development. These factors inter… Show more

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