Encyclopedia of Life Sciences 2009
DOI: 10.1002/9780470015902.a0021449
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Molecular Genetics of Predisposition to Respiratory Disorders in Newborn

Abstract: During the perinatal period, preterm neonates face severe complications. These include disorders of the lung such as respiratory distress syndrome and chronic lung disease. The risk of complications depends on maturity, but data also suggest the existence of an inherited susceptibility. This may be due to genetic polymorphisms and inherited mutations. Reported associations between lung disease and polymorphisms of genes encoding proteins that regulate inflammation, vasoregulation and lung development helped th… Show more

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