Encyclopedia of Life Sciences 2019
DOI: 10.1002/9780470015902.a0028464
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Molecular Genetics of Uterine Sarcomas

Abstract: Uterine sarcomas are a heterogeneous group of rare mesenchymal cancers, which includes tumours originating in both the smooth muscle of the myometrium and the endometrial stroma. They have variable course, although they are clinically aggressive as a group. Differentiating between various uterine sarcoma entities based on morphology and immunohistochemistry is feasible in many cases, but some specimens are challenging. Considerable knowledge has been gained in recent years regarding the molecular characteristi… Show more

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