Molecular imprinting micropolymerbeads having cooperative effect of both surfactant and inosine template

Abstract

Molecular imprinted polymer (MIP) microbeads were prepared by emulsion copolymerization of divinylbenzene (DVB) and methacrylic acid (MAA) in the presence of inosine (INO) template and laurylbenzenesulfonic acid (LBSA) as surfactant. The polymerization was carried out at 55 C under ultrasound exposure. The resulting copolymer microbeads, having 0.1-0.4 lm diameter, were observed to have a binding behavior of INO and surfactant to the polymer which was strongly dependent of the bulk pH; for example, at pH 3, 6, and 10 values of binding for INO to the imprinted copolymer were 3.7 lmol/g, 2.1 lmol/g, and 0 lmol/g, respectively.It was found that LBSA surfactant bound to the MIP microbeads similarly depending on pHs. At pH 3, 6, and 10, the LBSA values of binding were 23 lmol/g, 1.3 lmol/g, and 4.8 lmol/ g. It was also noted that the surfactant binding was enhanced in the presence of the INO template. This demonstrated that a cooperative binding with the surfactant was cooperatively occurred in the presence of INO.

Using molecularly imprinted polymeric spheres for hybrid membranes with selective adsorption of bisphenol A derivatives

“…Therefore, process improvements are needed depending on their purposes. For example, as reported previously, the MIP cross-linked powder prepared by dispersion with a surfactant showed influences on target recognition [5]. on the amounts of acetone.…”

“…To date, different methods to prepare imprinted spherical particles have been discovered and developed to overcome such problems. Polymerization procedures involving grafting [4], emulsion [5], dispersion [6,7], suspension [8] and multistep swelling [9] have been studied. However, in most cases, stabilizers, surfactants and additives can contaminate the final products [9].…”

A pH‐controllable imprinted composite membrane for selective separation of podophyllotoxin and its analog

“…The result showed in Figure 4 indicates that the adsorption capacity of MICM increases with the addition of functional monomer PMMP, suggesting that a higher content of PMMP would benefit the formation of PPT‐PMMP supermolecular complex. But as reported in the literature,17 excess functional monomer brought about more nonspecific binding sites. By comparison, MICM 2 prepared with 4 mmol PMMP exhibited the best specific recognition ability with an imprinting factor ( Q MICM / Q NICM ) of 1.76.…”

Optimization of Evodiamine-Imprinted Composite Membrane by Orthogonal Design Method

“…In general, the recognition ability of imprinted polymer towards template molecule depends on the preservation of the prepolymerized host-guest structure in a polymer matrix 15 . Therefore, it is important to investigate the interaction between template molecule and functional monomer in the pre-polymerization stage.…”