Molecular interactions of mussel protective coating protein, mcfp-1, from Mytilus californianus

Lu, Qingye; Hwang, Dong Soo; Liu, Yang; Zeng, Hongbo

doi:10.1016/j.biomaterials.2011.11.021

Cited by 97 publications

(94 citation statements)

References 41 publications

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“…For mfp-1 adhesion on mica, the significant hydroxyproline content could also contribute to the adhesion [18]. Thus, the hydrogen bonding follows the order of DOPA content in mol% ( of the additional contribution from hydroxyprolines in mfp-1, mfp-1 and mfp-3 may have similar hydrogen bonding strengths.…”

Section: Micamentioning

confidence: 97%

“…On the basis of a previously reported procedure [18,26,29], two thin and back-silvered mica sheets (1 -5 mm thick) were glued separately onto cylindrical silica discs (radius R ¼ 2 cm) and the exposed mica surfaces were directly used or further coated with different chemicals (i.e. SiO 2 , PMMA and PS) as follows.…”

Section: Preparation and Characterization Of Substrate Surfacesmentioning

confidence: 99%

“…The dissolution of K þ ions from mica and proton dissociation from mica and SiO 2 (pK a 7.0) makes these surfaces negatively charged [45]. Under the experimental conditions (0.35 M salt), the concentrated K þ ions in the solution can compete with the mfp molecules for adsorption sites on the substrate surfaces and thereby largely suppress the net electrostatic interaction energies [18]. Therefore, electrostatic interactions are not likely to play a major role in the adhesion of the three mfps under the experimental conditions used.…”

Section: Proposed Adhesion Mechanisms Of Mfps To Different Substratesmentioning

confidence: 99%

“…Therefore, electrostatic interactions are not likely to play a major role in the adhesion of the three mfps under the experimental conditions used. Hydrogen bonds can form between the hydroxyl or amine groups (hydrogen donors) on mfps and the oxygen atoms (hydrogen acceptors) on mica, SiO 2 [7,12,18]. However, it should be noted that water molecules in the solution are also able to form hydrogen bonds with the mfps and the substrates (so-called hydration layers).…”

Section: Proposed Adhesion Mechanisms Of Mfps To Different Substratesmentioning

confidence: 99%

“…In terms of the interaction energy, the cation -p interaction is comparable to hydrogen bonding while p-p stacking is weaker than hydrogen bonding [46 -49]. The cation-p interaction has recently been implicated in the adhesion of green mfp ( pvfp-1) [46] and mcfp-1 [18], which can probably also contribute to the adhesion of mfps to PS here.…”

Section: Proposed Adhesion Mechanisms Of Mfps To Different Substratesmentioning

confidence: 99%

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Adhesion of mussel foot proteins to different substrate surfaces

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Waite

et al. 2013

J. R. Soc. Interface.

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281

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Mussel foot proteins (mfps) have been investigated as a source of inspiration for the design of underwater coatings and adhesives. Recent analysis of various mfps by a surface forces apparatus (SFA) revealed that mfp-1 functions as a coating, whereas mfp-3 and mfp-5 resemble adhesive primers on mica surfaces. To further refine and elaborate the surface properties of mfps, the force-distance profiles of the interactions between thin mfp (i.e. mfp-1, mfp-3 or mfp-5) films and four different surface chemistries, namely mica, silicon dioxide, polymethylmethacrylate and polystyrene, were measured by an SFA. The results indicate that the adhesion was exquisitely dependent on the mfp tested, the substrate surface chemistry and the contact time. Such studies are essential for understanding the adhesive versatility of mfps and related/similar adhesion proteins, and for translating this versatility into a new generation of coatings and (including in vivo) adhesive materials.

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Section: Micamentioning

confidence: 97%

Section: Preparation and Characterization Of Substrate Surfacesmentioning

confidence: 99%