Molecular investigations of dengue virus during outbreaks in Orissa state, Eastern India from 2010 to 2011

Das, Biswadeep; Das, Mumani; Dwibedi, Bhagirathi; Kar, Supriya; Hazra, Rupenangshu K.

doi:10.1016/j.meegid.2013.03.016

Cited by 41 publications

(32 citation statements)

References 27 publications

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“…Co‐ or multiple infections of DENV heteroserotypes in the present study were also consistent in Thailand (Thavara et al and Mexico (Garcia‐Rejon et al 2011). DENV infection rate is higher for indoor than outdoor‐breeding Aedes in India (Das et al Virus‐infected mosquitoes correlate with the residences and workplaces of patients within dengue outbreak areas in Singapore (Chow et al However, field‐caught Ae. aegypti and Ae.…”

Section: Resultsmentioning

confidence: 99%

Natural vertical transmission of dengue viruses in Aedes aegypti in selected sites in Cebu City, Philippines

Edillo

Sarcos

Sayson

2015

Journal of Vector Ecology

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We attempted to determine the vertical transmission of dengue virus (DENV) in Aedes aegypti in selected sites in Cebu City, Philippines. Mosquito sub-adults were collected monthly from households and the field during the wet-dry-wet season from November, 2011 to July, 2012 and were laboratory-reared to adults. Viral RNA extracts in mosquitoes were assayed by hemi-nested RT-PCR. Results showed that 62 (36.26%; n=679) out of 171 mosquito pools (n=2,871) were DENV+. The minimum infection rate (MIR) of DENV ranged from 0 in wet months to 48.22/1,000 mosquitoes in April, 2012 (mid-dry). DENVs were detected in larvae, pupae, and male and female adults, with DENV-4, DENV-3, and DENV-1, in that rank of prevalence. DENV-1 co-infected with either DENV-3 or -4 or with both in April, 2012; DENV-3 and -4 were present in both seasons. More DENV+ mosquitoes were collected from households than in field premises (p<0.001) and in the dry than in the wet season (p<0.05), with significant interaction (p<0.05) between sites and premises but no interaction between sites and seasons (p>0.05). By Generalized Linear Mixed models, the type of premises nested in sites and monthly total rainfall were significant predictors of monthly dengue cases (p<0.05) and not MIR, season, temperature, and relative humidity. Surveillance of DENV prevalence in Ae. aegypti and detecting their natural foci in the dry season provide an early warning signal of dengue outbreak. Journal of Vector Ecology 40 (2): 282-291. 2015.

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Section: Resultsmentioning

confidence: 99%

Natural vertical transmission of dengue viruses in Aedes aegypti in selected sites in Cebu City, Philippines

Edillo

Sarcos

Sayson

2015

Journal of Vector Ecology

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“…In addition, the similarity of codon usage between DENV and Aedes vectors is generally higher than that between this virus and the primates, suggesting that the occurrence of the effect of the overall codon usage of Aedes vectors on that of DENV is, to some degree, prior to those of the primates. The successful human-to-human transmission depends on the secondary vector ( Aedes mosquitoes) and the transmission cycle between mosquitoes can be performed by the vertical transmission [36], [37], [38], [39]. The models of alternating infection of arthropods and vertebrates show substantial constraints on arbovirus evolution [40], [41].…”

Section: Resultsmentioning

confidence: 99%

The Distribution of Synonymous Codon Choice in the Translation Initiation Region of Dengue Virus

et al. 2013

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Dengue is the most common arthropod-borne viral (Arboviral) illness in humans. The genetic features concerning the codon usage of dengue virus (DENV) were analyzed by the relative synonymous codon usage, the effective number of codons and the codon adaptation index. The evolutionary distance between DENV and the natural hosts (Homo sapiens, Pan troglodytes, Aedes albopictus and Aedes aegypti) was estimated by a novel formula. Finally, the synonymous codon usage preference for the translation initiation region of this virus was also analyzed. The result indicates that the general trend of the 59 synonymous codon usage of the four genotypes of DENV are similar to each other, and this pattern has no link with the geographic distribution of the virus. The effect of codon usage pattern of Aedes albopictus and Aedes aegypti on the formation of codon usage of DENV is stronger than that of the two primates. Turning to the codon usage preference of the translation initiation region of this virus, some codons pairing to low tRNA copy numbers in the two primates have a stronger tendency to exist in the translation initiation region than those in the open reading frame of DENV. Although DENV, like other RNA viruses, has a high mutation to adapt its hosts, the regulatory features about the synonymous codon usage have been ‘branded’ on the translation initiation region of this virus in order to hijack the translational mechanisms of the hosts.

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“…are the principal carriers of dengue fever (DF) worldwide [2]. DF is a virally transmitted disease caused by Aedes mosquitoes in human [3].…”

Section: Aedes Mosquitoes Namely Aedes Aegypti and Aedes Albopictusmentioning

confidence: 99%

Incidence of dengue virus eruption in Swat, Khyber Pakhtunkhwa, Pakistan

Attaullah¹,

Iqbal²,

Khan³

et al. 2017

APJTD

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Molecular investigations of dengue virus during outbreaks in Orissa state, Eastern India from 2010 to 2011

Cited by 41 publications

References 27 publications

Natural vertical transmission of dengue viruses in Aedes aegypti in selected sites in Cebu City, Philippines

Natural vertical transmission of dengue viruses in Aedes aegypti in selected sites in Cebu City, Philippines

The Distribution of Synonymous Codon Choice in the Translation Initiation Region of Dengue Virus

Incidence of dengue virus eruption in Swat, Khyber Pakhtunkhwa, Pakistan

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