Molecular logic and computing

Abstract

Molecular substrates can be viewed as computational devices that process physical or chemical 'inputs' to generate 'outputs' based on a set of logical operators. By recognizing this conceptual crossover between chemistry and computation, it can be argued that the success of life itself is founded on a much longer-term revolution in information handling when compared with the modern semiconductor computing industry. Many of the simpler logic operations can be identified within chemical reactions and phenomena, as well as being produced in specifically designed systems. Some degree of integration can also be arranged, leading, in some instances, to arithmetic processing. These molecular logic systems can also lend themselves to convenient reconfiguring. Their clearest application area is in the life sciences, where their small size is a distinct advantage over conventional semiconductor counterparts. Molecular logic designs aid chemical (especially intracellular) sensing, small object recognition and intelligent diagnostics.

Dual-electrochromic bipolar electrode-based universal platform for the construction of various visual advanced logic devices

“…With the burgeoning developments of Boolean logic computation, various unconventional logic systems [1][2][3] have been constructed to operate different types of basic, 4-6 advanced 7-9 and concatenated molecular logic devices. [10][11][12] Although great research achievements have been realized in this area, there is still considerable room for progress.…”

Kinetic Model for a Threshold Filter in an Enzymatic System for Bioanalytical and Biocomputing Applications

“…[1][2][3][4][5][6][7][8][9][10][11][12][13][14] Such multi-input reaction cascades are used in biosensing, biomolecular computing, and decision making devices and setups utilizing (bio)chemical processes with well-defined responses. [15][16][17][18][19][20] These systems require experimental design and theoretical understanding [21][22][23] of chemical and biochemical reactions that allow signal response modification and control.…”

Development of a DNA sensor using a molecular logic gate

“…Basic logic operation of a molecular logic gate is the same as that of the electronic one, the only difference is in the input and output signal. Nowadays, these molecular logic gates can be used as simple as well as more complex devices [17][18][19] such as adders and subtractors [2][3][4], multiplexers/demultiplexers [5][6][7], encoders/decoders [8,9], keypad locks [10][11][12][13][14] etc. Among many applications of molecular logic gates, one of the most interesting is the investigation of the inside components of a cell, where silicon-based analogues are not expected to reach [2].…”