2024
DOI: 10.1007/s00018-024-05229-9
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Molecular mechanisms and therapeutic strategies for neuromuscular diseases

Alberto Andrea Zambon,
Yuri Matteo Falzone,
Alessandra Bolino
et al.

Abstract: Neuromuscular diseases encompass a heterogeneous array of disorders characterized by varying onset ages, clinical presentations, severity, and progression. While these conditions can stem from acquired or inherited causes, this review specifically focuses on disorders arising from genetic abnormalities, excluding metabolic conditions. The pathogenic defect may primarily affect the anterior horn cells, the axonal or myelin component of peripheral nerves, the neuromuscular junction, or skeletal and/or cardiac mu… Show more

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