2024
DOI: 10.26565/2075-5457-2024-42-2
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Molecular mechanisms and therapeutic strategies of Naegleria fowleri Carter (1970): a review of the fatal brain-eating amoeba

N. Datta

Abstract: Naegleria fowleri is a thermophilic free-living amoeba that can cause a rare and fatal infection of the brain called primary amoebic meningoencephalitis (PAM). PAM is a serious public health concern, as it affects mostly young and healthy individuals who are exposed to warm freshwater environments, and has a mortality rate of approximately 98%. The infection occurs when the amoeba enters the nasal cavity during swimming or other recreational activities, and migrates to the brain through the olfactory nerve. In… Show more

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