Molecular Pathology of Pancreatic Cystic Lesions with a Focus on Malignant Progression
Yan Hu,
Dan Jones,
Ashwini K. Esnakula
et al.
Abstract:The malignant progression of pancreatic cystic lesions (PCLs) remains understudied with a knowledge gap, yet its exploration is pivotal for effectively stratifying patient risk and detecting cancer at its earliest stages. Within this review, we delve into the latest discoveries on the molecular level, revealing insights into the IPMN molecular landscape and revised progression model, associated histologic subtypes, and the role of inflammation in the pathogenesis and malignant progression of IPMN. Low-grade PC… Show more
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