Molecular phylogenetic analysis for Ovis aries with whole mitochondrial genome sequencing

Abstract

Domestication of Ovis aries has taken place time immorial across the different geographical regions across the globe. Biodiversity among the sheep population has been interesting to study by a group of researchers based on mitochondrial genes like Cytochrome B, D loop. The current study is a novel attempt to understand the molecular phylogenomics among Ovis aries through all the 37 genes of mitochondria. We have analyzed complete mitochondrial genome sequencing for sheep breeds for West Bengal as Garole, Chotanagpuri, Bonpala and Birbhum sheep. Phylogenetic analysis reveals genetic similarity between Garole and Chotanagpuri brred of sheep, where as Birbhum and Bonpala were found to be genetically distinct. Phylogenomics in a global prospect reveal three lineages, Lineage A comprise of sheep from West Bengal grouped with Tibetan sheep. Lineage B consists of sheep population across the other parts including Europe (France, Denmark), Africa and Syro- Arabian desert, whereas Lineage C emerged as smaller outgroup.

Role of NUMTs (Nuclear mitochondrial DNA) genes in affecting disease resistance in duck against Pasteurellosis

“…In our earlier studies, we could explore certain immune response genes against parasitic infestation in sheep model (reference) and against bacterial (Chakraborty et al, 2023), viral (Pal et al,2021 and Pal et al, 2020) in chicken and duck model (Pal et al, 2022). Simultaneously, we have also detected certain genes of mitochondrial origin, which are responsible for disease resistance in sheep (Banerjee et al, 2021, Rawat et al, 2021), chicken and duck model (Pal et al, 2020, Pal et al, 2021,Pal et al, 2022). In the following research work, it was attempted to study a novel area of role of certain nuclear genes that act through mitochondria (Chakraborty et al, 2023).…”

Phylophenomic and Phylogenomic analysis for Ovis aries reveals distinct identity of newly reported breed

“…In our lab, we had reported the phylogenetic analysis for sheep initially with mitochondrial gene as Cytochrome B 2 . Later on, phylogenomic analysis for sheep were conducted with complete mitochondrial genome 3 . Indigenous breeds of sheep are mostly adapted to their local climatic conditions and somewhat resistant to diseases.…”