Molecular phylogeny and divergence times of the genus Hedysarum (Fabaceae) with special reference to section Multicaulia in Southwest Asia

Nafisi, Haniyeh; Osaloo, Shahrokh Kazempour; Mozaffarian, Valiollah; Schneeweiss, Gerald M.

doi:10.1007/s00606-019-01620-3

Cited by 25 publications

(57 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…At the same time, both the cp and nr trees resolved the sect. Hedysarum as a monophyletic clade [ 33 , 35 ]. The species of the sect.…”

Section: Discussionmentioning

confidence: 99%

“…These similarities in distribution of major 45S and 5S rDNA clusters are consistent with the monophyletic origin of the sect. Hedysarum [ 33 , 35 ]. Besides, in karyotypes of the species from groups 2, 3, and 4, additional 5S and 45S rDNA clusters were revealed on other chromosome pairs, which can be related to chromosome rearrangements as well as intra- and interspecific hybridization events occurred during speciation.…”

Section: Discussionmentioning

confidence: 99%

“…Currently, taxonomic and phylogenetic relationships within the genus Hedysarum are being studied intensively with the use of various molecular phylogenetic approaches [ 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 ]. Recent extensive phylogenetic studies of Hedysareae based on nuclear (ITS, ETS, PGDH, SQD1, TRPT) and plastid (psbA-trnH, trnC-petN, trnL-trnF, trnS-trnG, petN-psbM) DNA sequencing did not support the monophyly of the genus Hedysarum [ 33 , 34 , 35 ]. Duan et al [ 33 ], using nrDNA ITS and three plastid regions ( mat K, trn L–F, trn H– psb A), recognized three clades within the genus Hedysarum corresponding to the sections Hedysarum , Multicaulia , and Stracheya .…”

Section: Introductionmentioning

confidence: 99%

“…At the same time, within the sect. Hedysarum , comparative analyses of nuclear and plastid genome sequences have been performed only in few species, and genomes of a number closely related medicinal species distributed in Eurasia still remain unstudied [ 33 , 34 , 35 ], and comprehensive investigation of cytogenetic peculiarities is essential for clarifying their taxonomy and phylogenetic relationships.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Molecular Cytogenetics of Eurasian Species of the Genus Hedysarum L. (Fabaceae)

Yurkevich

Samatadze

Selyutina

et al. 2021

Plants

View full text Add to dashboard Cite

The systematic knowledge on the genus Hedysarum L. (Fabaceae: Hedysareae) is still incomplete. The species from the section Hedysarum are valuable forage and medicinal resources. For eight Hedysarum species, we constructed the integrated schematic map of their distribution within Eurasia based on currently available scattered data. For the first time, we performed cytogenomic characterization of twenty accessions covering eight species for evaluating genomic diversity and relationships within the section Hedysarum. Based on the intra- and interspecific variability of chromosomes bearing 45S and 5S rDNA clusters, four main karyotype groups were detected in the studied accessions: (1) H.arcticum, H. austrosibiricum, H. flavescens, H. hedysaroides, and H. theinum (one chromosome pair with 45S rDNA and one pair bearing 5S rDNA); (2) H. alpinum and one accession of H. hedysaroides (one chromosome pair with 45S rDNA and two pairs bearing 5S rDNA); (3) H. caucasicum (one chromosome pair with 45S rDNA and one chromosome pair bearing 5S rDNA and 45S rDNA); (4) H. neglectum (two pairs with 45S rDNA and one pair bearing 5S rDNA). The species-specific chromosomal markers detected in karyotypes of H. alpinum, H. caucasicum, and H. neglectum can be useful in taxonomic studies of this section.

show abstract

“…At the same time, both the cp and nr trees resolved the sect. Hedysarum as a monophyletic clade [ 33 , 35 ]. The species of the sect.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Molecular Cytogenetics of Eurasian Species of the Genus Hedysarum L. (Fabaceae)

Yurkevich

Samatadze

Selyutina

et al. 2021

Plants

View full text Add to dashboard Cite

show abstract

“…Multicaulia (Boiss.) B.Fedtsch., and recent phylogenetic studies (Duan et al, 2015;Liu et al, 2017;Nafisi et al, 2019) indicated that this section is composed of 2 clades of traditionally recognized subsects: Multicaulia, Subacaulia (Boiss.) B.H.…”

Section: Introductionmentioning

confidence: 96%

Hedysarum alamutense (Fabaceae-Hedysareae), a new species from Iran, and its phylogenetic position based on molecular data

Nafisi¹,

Osaloo²,

Mozaffarian³

et al. 2019

Turk J Bot

Self Cite

View full text Add to dashboard Cite

Hedysarum alamutense, a new species in the tribe Hedysareae DC. (Fabaceae), is described and illustrated. It belongs to the traditionally recognized Hedysarum L. section Multicaulia (Boiss.) B.Fedtsch., which extends over the West Alborz Mountains in northern Iran. This species is characterized by greenish stems and corolla persisting in fruiting stage and has mostly 1-2-jointed, unarmed, biconvex pods with short hairs becoming bald early, and flattened margins. Phylogenetic analyses of molecular data clearly unite this species with H. formosum Fisch. & C.A.Mey. ex Basin. The new species is characterized by 4 singleton nucleotide substitutions, suggesting it as a distinct taxon. Phylogenetic inferences are consistent with the interpretations of morphological features. Moreover, the lack of nucleotide variation among individual samples of H. formosum indicated that the species has not been diversified at the population level and reinforced our findings.

show abstract

A Biochemical Approach for Hedysarum candidissimum from Turkey: Screening Phytochemicals, Evaluation of Biological Activites, and Molecular Docking Study

Altay

Yeniçeri

Taslimi

et al. 2022

Chemistry & Biodiversity

View full text Add to dashboard Cite

This study was designed to screen the phytochemical composition and investigate the biological activities of Hedysarum candidissimum extracts and also support the results with molecular docking studies. LC/MS/MS analysis revealed the presence of 22 phytochemical constituents (mainly phenolic acids, flavonoids, and flavonoid glycosides) in the plant structure. The methanol extract exhibited the strongest antioxidant activity among all the extracts with its strong DPPH radical scavenging and iron reducing capacity, as well as high phenolic and flavonoid contents. Additionally, it was found to be the most promising acetylcholinesterase (AChE: IC 50 : 93.26 μg/mL) and α-glycosidase (AG: IC 50 : 28.57 μg/mL) inhibitory activities, supported by the major phenolics of the species through in silico studies. Ethyl acetate extract had the strongest cytotoxic effect on HT-29 (IC 50 : 63.03 μg/mL) and MDA-MB-453 (IC 50 : 95.36 μg/mL) cancer cell lines. Both extracts exhibited considerable apoptotic and anti-migrative effects on HT-29 cells. The investigations provide phyto-analytical and biopharmacological results which can be extended by in vivo studies in the future.

show abstract

Molecular phylogeny and divergence times of the genus Hedysarum (Fabaceae) with special reference to section Multicaulia in Southwest Asia

Cited by 25 publications

References 51 publications

Molecular Cytogenetics of Eurasian Species of the Genus Hedysarum L. (Fabaceae)

Molecular Cytogenetics of Eurasian Species of the Genus Hedysarum L. (Fabaceae)

Hedysarum alamutense (Fabaceae-Hedysareae), a new species from Iran, and its phylogenetic position based on molecular data

A Biochemical Approach for Hedysarum candidissimum from Turkey: Screening Phytochemicals, Evaluation of Biological Activites, and Molecular Docking Study

Contact Info

Product

Resources

About