Molecular proof for Lophomonas infection in a patient with history of breast cancer

Abstract

We report a 52‐year‐old patient with a history of breast cancer (BC) referred to the clinic of Afzalipour Hospital, in Kerman, eastern Iran, with a 1‐week complaint of restless dyspnea. A chest computed tomography scan revealed consolidations in the upper lobes of both lungs. The patient had no history of smoking or underlying diseases that would predispose her to consolidation, including pneumonia. Then, bronchoscopy was performed for the patient, and bronchoalveolar lavage fluid was sent to the Iranian National Registry Center, where the Lophomonas parasite was detected in the sample and confirmed using a polymerase chain reaction test. Finally, her symptoms improved by receiving oral metronidazole three times a day for 3 weeks.

Paraneoplastic acute eosinophilic pneumonia due to carotid angiosarcoma: A rare case

“…Previous HRCT studies of AEP patients reported that 70%–90% had interlobular septal thickening and almost all had bilateral ground glass attenuation in addition to bilateral pleural effusion in more than 90% of cases 13 . There are no official diagnostic criteria; however, the modified Philit criteria has been used for AEP diagnosis, which includes some clinical factors (length of fever and hypoxemia), radiologic findings (bilateral diffuse pulmonary infiltrates on chest radiography), paraclinical results (BAL fluid eosinophilia and/or infiltrations of eosinophils in the lung parenchyma on lung biopsy), and a lack of known causes of eosinophilic lung disease such as infection and drugs 14,15 . AEP patients often experience progressive respiratory failure or severe hypoxia; however, intravenous high‐dose systemic corticosteroid therapy dramatically improves their condition within days 14 .…”