Molecular Rearrangement of 2‐Substituted Indazolones: Unorthodox Access to 2‐Carboxylate‐2,3‐dihydroquinazolin‐4‐(1H)‐one Scaffold

Abstract

We disclose a practical and efficient strategy for the expedient synthesis of 2,3-dihydroquinazolin-4-(1H)-one derivatives by one carbon insertion into cyclic NÀ N bond. Spontaneous manipulations with operationally simple procedures furnishing pharmaceutically useful compounds are key features of the developed protocol. Mechanistic studies [a] C.