Molecular recognition and sensing of dicarboxylates and dicarboxylic acids

Abstract

This review outlines challenges faced in recognition and detection of dicarboxylic acids and dicarboxylates and strategies used to obtain effective and observable interactions in the period from 2014 to 2020.

Chiroptical Enhancement of Chiral Dicarboxylic Acids from Confinement in a Stereodynamic Supramolecular Cage

“…In recent years, we have been interested in carboxylic acids sensing 26 − 29 using TPMA -based supramolecular cages. 30 − 32 The high affinity and selectivity of our system toward diacids, together with the capability to form in complex mixtures, prompted us to investigate if it was possible to take advantage also of the stereodynamic features of the two TPMA units in chiral sensing.…”

“…In recent years, we have been interested in carboxylic acids sensing − using TPMA -based supramolecular cages. − The high affinity and selectivity of our system toward diacids, together with the capability to form in complex mixtures, prompted us to investigate if it was possible to take advantage also of the stereodynamic features of the two TPMA units in chiral sensing. − For these reasons, we investigated the recognition capabilities and chiroptical properties of the molecular cage 1 toward: l -malic acid ( l - Mal ), l -tartaric acid ( l - Tar ), the amino acids Boc - l -glutamic acid ( l - Glu ), Boc - l -aspartic acid ( l - Asp ), and (1 R ,3 S )-camphoric acid ( R , S - Cam ).…”

The Chloroazaphosphatrane Motif for Halogen Bonding in Solution

“…Anion recognition plays a crucial role in medicine, biology, chemistry, and environmental sciences. , Synthetic anion receptors have thus found various applications, ranging from sensors, organocatalysts, or anion carriers in living systems to the remediation of toxic or radioactive anions from aqueous wastes. − As a consequence, the development of new motifs for anion binding arouses a considerable interest. Behind the traditional interactions often used to recognize anions, such as hydrogen bonding, dispersion forces, or electrostatic interactions, less common interactions, like anion−π interactions, − coordination with Lewis acid (metals or main group elements), − or σ–hole interactions − have recently received growing attention, leading to the expansion of anion receptors and to the improvement of the selectivity and binding strength.…”

Probing E/Z Isomerism Using Pillar[4]pyridinium/Gold Nanoparticle Ensembles and Their Photoresponsive Behavior

“…Given the similar appearance but distinct functions of these acids, the spatiotemporal differentiation of each is of vast importance for their proper use and effectiveness. Despite several reports on detecting butenedioic acid, − a general strategy for the recognition of E/Z diacids has not yet been developed.…”