2024
DOI: 10.1101/2024.02.08.24302515
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Molecular signatures of chronic antibody-mediated rejection in human liver transplants

Bastian Engel,
Ahmed Alaswad,
Alejandro Campos-Murguia
et al.

Abstract: Background&Aims: The role of antibody-mediated rejection (ABMR) after liver transplantation (LT) remains controversial. Chronic ABMR (cABMR) is often subclinical and potentially missed without surveillance biopsies (svLbx) which are not established in most LT centers. Transcriptome analysis previously characterized molecular changes in T cell-mediated rejection (TCMR) after solid organ transplantation. We aimed to identify molecular cABMR signatures after LT for a more comprehensive understanding of cABMR.… Show more

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