Molecular structure of l-lysyl-l-tyrosyl-l-serine acetate

The ability of lower peptides to form co-crystals: inclusion compounds of Leu-Leu-Leu tripeptide with pyridine and picolines

“…The inclusion compounds of L-glycyl-L-leucyl-L-tyrosine, (GLT) 2 *(DMSO)*5(H 2 O) (7), 12 (GLT) 2 *(DMSO)*2.5(H 2 O) (8), 13 and (GLT) 2 *(isopropanol)*2(H 2 O) (9), 15 and an inclusion compound of L-lysyl-L-tyrosyl-L-serine, (KTS) 2 *3(acetate)*(acetic acid)*(isopropanol) (10), 14 display certain similarities to compounds 1-4. All four inclusion compounds crystallize in the P1 space group and the three GLT inclusions, 7-9, are isostructural.…”

“…One solvate of the tripeptide has already been reported, (LLL) 2 *3(CH 3 OH)*(H 2 O) 11 and a few solvates of other related tripeptides have been isolated and studied. [12][13][14][15][16] As co-crystals with aromatic solvents have not been reported before, pyridine and picolines (methylpyridines) were used in this study as both are typical aromatic molecules and simpler counterparts of their more complex bioactive derivatives, such as nicotine and nicotinamide (vitamine B 3 ).…”