Molecular survey of basidiomycetes and divergence time estimation: An Indian perspective

Bhatt, Meghna; Mistri, Pankti; Joshi, Ishita; Ram, Hemal; Raval, Rinni; Thoota, Sruthi; Patel, Ankur M.; Raval, Dhrupa; Bhargava, Poonam; Soni, Subhash; Bagatharia, S. B.; Joshi, Madhvi

doi:10.1371/journal.pone.0197306

Cited by 8 publications

(4 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Two Orders are encompassed by Dikarya, the Basidiomycota and the Ascomycota, and both can play significant roles in wood and/or coating degradation. Ongoing research suggests that both Basidiomycota and Ascomycota evolved from earlier progenitor fungi between 400 and 500 million years ago [28][29][30][31], with species of white rot fungi that had the ability to decay lignocellulose evolving only perhaps 280 million years ago within a Class of fungi known as the Agaricomycetes [31]. Present day Agaricomycetes include many well-known mushroom-producing species, but many of the Agaricomycetes are rather nondescript in their macroscopic features, yet they have the ability to aggressively attack wood and disrupt any overlying coating materials.…”

Section: Biology and Evolutionmentioning

confidence: 99%

Fungal Degradation of Wood: Emerging Data, New Insights and Changing Perceptions

2020

View full text Add to dashboard Cite

Wood durability researchers have long described fungal decay of timber using the starkly simple terms of white, brown and soft rot, along with the less destructive mold and stain fungi. These terms have taken on an almost iconic meaning but are only based upon the outward appearance of the damaged timber. Long-term deterioration studies, as well as the emerging genetic tools, are showing the fallacy of simplifying the decay process into such broad groups. This paper briefly reviews the fundamentals of fungal decay, staining and mold processes, then uses these fundamentals as the basis for a discussion of fungal attack of wood in light of current knowledge about these processes. Biotechnological applications of decay fungi are reviewed, and an overview is presented on how fungi surmount the protective barriers that coatings provide on surfaces. Advances in biochemical analyses have, in some cases, radically altered our perceptions of how wood is degraded, and even the relationships between fungal species, while other new findings have reinforced traditional perspectives. Suggestions for future research needs in the coatings field relative to enhanced fungal and environmental protection are presented.

show abstract

Section: Biology and Evolutionmentioning

confidence: 99%

Fungal Degradation of Wood: Emerging Data, New Insights and Changing Perceptions

2020

View full text Add to dashboard Cite

show abstract

“… 4 Among the Ganoderma species, G. multipileum was discovered on a stump of decaying wood for the first time in Taiwan. 5 Since then, G. multipileum has been described based on morphology and phylogeny in subtropical and tropical countries such as China, 6 – 8 India, 9 Pakistan, 10 and Thailand. 11 In previous reports, G. multipileum was described as a white-rot fungus that mainly decays dead softwood such as Sterculia nobilis , Delonix regia , 5 and Pinus merkusii , 11 as well as hardwood plants such as Dalbergia sissoo and Vachellia nilotica.…”

Section: Introductionmentioning

confidence: 99%

Phylogenetic analysis and morphology of Ganoderma multipileum, a Ganoderma species associated with dieback of the metropolitan woody plant Delonix regia (Boj. ex Hook.) Raf. in Vietnam

Nguyen,

Bui

et al. 2023

Science Progress

View full text Add to dashboard Cite

Ganoderma multipileum, a wood decay mushroom, was initially discovered and classified in Taiwan through the analysis of its morphology and the internal transcribed spacer (ITS) region of nuclear ribosomal DNA. In this study, we identified a mushroom associated with the dieback of Delonix regia (Boj. ex Hook.) Raf., a woody ornamental street tree in Vietnam, as Ganoderma multipileum. This classification was based on phylogenetic analysis of ITS, RPB2, and TEF1 sequences, as well as morphology assessment and scanning electron microscope observation of basidiospores. The phylogenetic analysis revealed that the specimens collected in Vietnam formed a monophyletic group of Ganoderma multipileum with a high bootstrap value and posterior probability (100%/1.00). Furthermore, the morphological features consistent with laccate Ganoderma, including a thin pileipellis composed of enlarged and bulbous hyphae, and the basidiomes exhibited two different phenotypes. Notably, scanning electron microscopy of the basidiospores revealed ovoid spores with numerous echinules, providing the first documented evidence of this characteristic for Ganoderma multipileum. This research represents the first recorded instance of Ganoderma multipileum in Vietnam associated with the dieback of Delonix regia.

show abstract

“…Homologs of the Pas2/Rds2 complex exist in ascomycetous fungi such as S. cerevisiae ( 26 , 27 ) and A. nidulans ( 28 , 29 ), although their role in hypoxia adaptation has not been tested. Given that basidiomycetes such as Cryptococcus diverged from ascomycetes from a common ancestor at least 600 million years ago ( 30 ), the Pas2/Rds2 complex and its regulatory pathways might be conserved among diverse fungal species. Future investigation into the relationship between the Pas2/Rds2 complex and other regulators identified in different species could reveal the conserved and distinct features of metabolism rewiring in response to hypoxia.…”

Section: Introductionmentioning

confidence: 99%

A PAS Protein Directs Metabolic Reprogramming during Cryptococcal Adaptation to Hypoxia

Zhao

Lin

2021

mBio

View full text Add to dashboard Cite

To aerobic organisms, low oxygen tension (hypoxia) presents a physiological challenge. To cope with such a challenge, metabolic pathways such as those used in energy production have to be adjusted. Many of such metabolic changes are orchestrated by the conserved hypoxia-inducible factors (HIFs) in higher eukaryotes. However, there are no HIF homologs in fungi or protists, and not much is known about conductors that direct hypoxic adaptation in lower eukaryotes. Here, we discovered that the transcription factor Pas2 controls the transcript levels of metabolic genes and consequently rewires metabolism for hypoxia adaptation in the human fungal pathogen Cryptococcus neoformans. Through genetic, proteomic, and biochemical analyses, we demonstrated that Pas2 directly interacts with another transcription factor, Rds2, in regulating cryptococcal hypoxic adaptation. The Pas2/Rds2 complex represents the key transcription regulator of metabolic flexibility. Its regulation of metabolism rewiring between respiration and fermentation is critical to our understanding of the cryptococcal response to low levels of oxygen. IMPORTANCE C. neoformans is the main causative agent of fungal meningitis that is responsible for about 15% of all HIV-related deaths. Although an obligate aerobic fungus, C. neoformans is well adapted to hypoxia conditions that the fungus could encounter in the host or the environment. The sterol regulatory element binding protein (SREBP) is well known for its role in cryptococcal adaptation to hypoxia through its regulation of ergosterol and lipid biosynthesis. The regulation of metabolic reprogramming under hypoxia, however, is largely unknown. Here, we discovered one key regulator, Pas2, that mediates the metabolic response to hypoxia together with another transcription factor, Rds2, in C. neoformans. The findings help define the molecular mechanisms underpinning hypoxia adaptation in this and other lower eukaryotes.

show abstract

Molecular survey of basidiomycetes and divergence time estimation: An Indian perspective

Cited by 8 publications

References 36 publications

Fungal Degradation of Wood: Emerging Data, New Insights and Changing Perceptions

Fungal Degradation of Wood: Emerging Data, New Insights and Changing Perceptions

Phylogenetic analysis and morphology of Ganoderma multipileum, a Ganoderma species associated with dieback of the metropolitan woody plant Delonix regia (Boj. ex Hook.) Raf. in Vietnam

A PAS Protein Directs Metabolic Reprogramming during Cryptococcal Adaptation to Hypoxia

Contact Info

Product

Resources

About