2024
DOI: 10.1038/s41419-024-06734-2
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Molecular understanding and clinical outcomes of CAR T cell therapy in the treatment of urological tumors

Gong Zhang,
Yuan Wang,
Shiyang Lu
et al.

Abstract: Chimeric antigen receptor engineered T (CAR T) cell therapy has developed rapidly in recent years, leading to profound developments in oncology, especially for hematologic malignancies. However, given the pressure of immunosuppressive tumor microenvironments, antigen escape, and diverse other factors, its application in solid tumors is less developed. Urinary system tumors are relatively common, accounting for approximately 24% of all new cancers in the United States. CAR T cells have great potential for urina… Show more

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