Molecularly Imprinted Electrochemical Sensors

Suryanarayanan, V.; Wu, Cheng-Tar; Ho, Kuo–Chuan

doi:10.1002/elan.200900616

Cited by 219 publications

(92 citation statements)

References 153 publications

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“…MIP based sensors have been discussed as promising materials for different fields such as clinical, bioanalytical, process control and environmental applications [58]. A sensor itself is defined as a device that comprises a recognition element and a transducer that converts the chemical information into measurable signal [59].…”

Section: Mip Based Sensorsmentioning

confidence: 99%

Applications of molecularly imprinted polymers to the analysis and removal of personal care products: A review

Figueiredo

Erny

Santos

et al. 2016

Talanta

145

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Personal-care products (PCPs) involve a variety of chemicals whose persistency along with their constant release into the environment raised concern to their potential impact on wildlife and humans health. Regarded as emergent contaminants, PCPs demonstrated estrogenic activity leading to the need of new methodologies to detect and remove those compounds from the environment.Molecular imprinting starts with a complex between a template molecule and a functional monomer, which is then polymerized in the presence of a cross-linker. After template removal, the polymer will contain specific cavities. Based on a good selectivity towards the template, molecularly imprinted polymers (MIPs) have been investigated as efficient materials for the analysis and extraction of the so called emergent pollutants contaminants.Rather than lowering the limit of detections, the key theoretical advantage of MIP over existing methodologies is the potential to target specific chemicals. This unique feature, sometime named specificity (as synonym to very high selectivity) allows to use cheap, simple and/or rapid quantitative techniques such as fast separation with ultra-violet (UV) detection, sensors or even spectrometric techniques. When a high degree of selectivity is achieved samples extracted with MIPs can be directly analysed without the need of a separation step. However, while some papers clearly demonstrated the specificity of their MIP toward the targeted PCP, such prove is often lacking, especially with real matrices, making it difficult to assess the success of the different approaches.This review paper focusses on the latest development of MIPs for the analysis of personal care products in the environment, with particular emphasis on design, preparation and practical applications of MIPs.3

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Section: Mip Based Sensorsmentioning

confidence: 99%

Applications of molecularly imprinted polymers to the analysis and removal of personal care products: A review

Figueiredo

Erny

Santos

et al. 2016

Talanta

145

View full text Add to dashboard Cite

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“…[1][2][3][4] Molecular imprinting electrochemical sensor (MIECS), which combined the MIT and electrochemical sensor, inhibited high selectivity and sensitivity by using molecular imprinting polymers (MIPs) as specific recognition element for template molecule. Up to now, MIECSs have been successfully used to imprint small biomolecules.…”

Section: Introductionmentioning

confidence: 99%

Surface molecular imprinted electrochemical sensor for lysozyme based on metal coordinate technology

Chen¹,

Bao²,

Li³

et al. 2018

Proceedings of the 4th Annual International Conference on Material Engineering and Application (ICMEA 2017)

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Abstract-A novel and efficient molecular imprinted polymers (MIPs) electrochemical sensor based on metal coordination technology was prepared by electro-polymerization, which was applied as a molecular recognition element to modify glassy carbon electrode (GCE) to construct an electrochemical sensor (MIPs/IDA/GR/GCE) for sensitive detection of lysozyme (Lyz). The prepared MIPs/IDA/GR/GCE showed a fast rebinding dynamics, which was successfully applied to Lyz detection with a wide linear range from 1.0 ×10 -11 to 1.0 × 10 -5 g/L (R=0.998) and a detection limit of 2.3 × 10 -12 g/L. Moreover, the fabricated sensor possessed a good selectivity and sensitivity, providing a promising tool for immunoassays and clinical applications.

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“…Moreover, determination and monitoring of a wide range of analytes based on electrochemical techniques has made 4 electrochemical transducers very popular due to the ease of measurement and the ready availability of instrumentation. They also offer good limits of detection at low cost with the possibility of easy miniaturisation and automation (Suryanarayanan et al, 2010;Piletsky and Turner, 2002;Merkoci and Alegret, 2002).…”

Section: Introductionmentioning

confidence: 99%

Electrochemical evaluation of troponin T imprinted polymer receptor

Karimian

Turner

Tiwari

2014

Biosensors and Bioelectronics

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The selective detection and quantification of macromolecular targets is a fundamental biological mechanism in nature. Molecularly imprinted polymers (MIPs) have been identified as one of the most promising synthetic alternatives to bioreceptors. However, expanding this methodology towards selective recognition of bulky templates such as proteins appears to be extremely challenging due to problems associated with removal of the template from the polymeric network. In this study, polymer imprinted with troponin T (TnT) was assessed using

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Molecularly Imprinted Electrochemical Sensors

Cited by 219 publications

References 153 publications

Applications of molecularly imprinted polymers to the analysis and removal of personal care products: A review

Applications of molecularly imprinted polymers to the analysis and removal of personal care products: A review

Surface molecular imprinted electrochemical sensor for lysozyme based on metal coordinate technology

Electrochemical evaluation of troponin T imprinted polymer receptor

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