Molecularly imprinted polymer as a novel solid‐phase microextraction coating for the selective enrichment of trace imidazolinones in rice, peanut, and soil

Zhao

J of Separation Science

et al. 2016

Molecularly imprinted polymeric microspheres with a high recognition ability toward the template molecule, ellagic acid, were synthesized based on distillation-precipitation polymerization. The as-obtained polymers were characterized by scanning electron microscopy, infrared spectroscopy, and thermogravimetric analysis. Static, dynamic, and selective binding tests were adopted to study the binding properties and the molecular recognition ability of the prepared polymers for ellagic acid. The results indicated that the maximum static adsorption capacity of the prepared polymers toward ellagic acid was 37.07 mg/g and the adsorption equilibrium time was about 100 min when the concentration of ellagic acid was 40 mg/mL. Molecularly imprinted polymeric microspheres were also highly selective toward ellagic acid compared with its analogue quercetin. It was found that the content of ellagic acid in the pomegranate peel extract was enhanced from 23 to 86% after such molecularly imprinted solid-phase extraction process. This work provides an efficient way for effective separation and enrichment of ellagic acid from complex matrix, which is especially valuable in industrial production.

Section: Introductionmentioning

confidence: 99%

Preparation of ellagic acid molecularly imprinted polymeric microspheres based on distillation–precipitation polymerization for the efficient purification of a crude extract

Zhao

J of Separation Science

et al. 2016

Journal of Analytical Methods in Chemistry

“…Molecular imprinting technology (MIT) is a new technology based on the antigen-antibody theory, which has foundations in biochemistry, polymer chemistry, and material science, as well as other disciplines [18][19][20][21]. Molecular imprinted polymers (MIPs) are functional materials with specific recognition abilities and have been widely used in the detection of CAP residues in various matrices such as milk, milk powder, serum, honey, shrimp, and urine [22].…”

Section: Introductionmentioning

confidence: 99%

Preparation of Restricted Access Media-Molecularly Imprinted Polymers for the Detection of Chloramphenicol in Bovine Serum

Zhao

Chanling

Sun

et al. 2019

Chloramphenicol-(CAP-) restricted access media-molecularly imprinted polymers (CAP-RAM-MIPs) were prepared by precipitation polymerization using CAP as a template molecule, 2-diethylaminoethyl methacrylate (DEAEM) as a functional monomer, ethylene glycol dimethyl acrylate (EDMA) as a crosslinking agent, glycidyl methacrylate (GMA) as an outer hydrophilic functional monomer, and acetonitrile as a pore former and solvent. e CAP-RAM-MIPs were successfully characterized by Fourier-transform infrared spectroscopy, scanning electron microscopy, and thermogravimetric analysis. e adsorption performance was investigated in detail using static, dynamic, and selective adsorption experiments. Adsorption equilibrium could be reached within 11 min. e CAP-RAM-MIPs had a high adsorption rate and good specific adsorption properties. Scatchard fitting curves indicated there were two binding sites for CAP-RAM-MIPs. Adsorption was Freundlich multilayer adsorption and consistent with the quasi-second kinetic model. Using CAP-RAM-MIPs for selective separation and enrichment CAP in bovine serum in combination with highperformance liquid chromatography (HPLC), CAP recovery ranged from 94.1 to 97.9% with relative standard deviations of 0.7-1.5%.is material has broad application prospects in enrichment and separation.

“…SPME is generally based on the partition of target analytes between the sample and the coating materials, which are critical in SPME performance . Up to now, various application purposes of coating fibers for SPME have been appearing in succession, such as commercially available polydimethylsiloxane (PDMS) and polyacrylate (PA), home‐made divinylbenzene sol–gel copolymer, graphene , ionic liquid , polyaniline , organic‐inorganic hybrid nanocomposite , metal‐organic framework , selective molecularly imprinted polymer (MIP) coating , and even substrateless MIP monolithic fibers (MF) . MIP‐MF owns higher extraction capacity and stability as compared with MIP coating on a silica or metal steel.…”

Section: Introductionmentioning

confidence: 99%

Ultrasensitive determination of highly polar trimethyl phosphate in environmental water by molecularly imprinted polymeric fiber headspace solid‐phase microextraction

Cai

J of Separation Science

Deng

et al. 2018

A sensitive, accurate, and cost effective method for the quantification of trimethyl phosphate, which is highly polar and volatile, in environmental water is presented. Trimethyl phosphate was headspace solid-phase microextracted on a molecularly imprinted polymeric fiber, and then the fiber was thermally desorbed in the gas chromatograph injector, and the compound was determined. The trimethyl phosphate imprinted polymeric fiber was prepared by copolymerization in a fused silica capillary tube and obtained by removal of the wall of fused silica capillary tube. The monolithic fiber displayed good selectivity toward trimethyl phosphate among its structural analogues. It was thermally stable up to 320°C so that it can withstand the high temperature of the gas chromatograph injector for desorption. The factors influencing the performance of its headspace solid-phase microextraction were studied. Under the optimal conditions, the method for quantification of trimethyl phosphate in environmental water was well developed. It exhibited significant linearity, the lowest limit of quantification to date, and good recoveries. Using this method, trimethyl phosphate was detected in five out of seven environmental water samples at concentration levels from 0.28 to 1.22 μg/L, illustrating the heavy pollution of trimethyl phosphate in environmental water.