Molecularly imprinted self-assembled films with specificity to cholesterol

Toward protein imprinting with polymer brushes

“…11 These 2D approaches typically rely on the initial interactions between surface and template functionalities. For instance, Shi et al 12 reported a technique to surface imprint proteins in a plasma deposited polymer film.…”

Development of an Electrochemical Cholesterol Sensor System for Food Analysis

“…Washing out the cholesterol with ethanol leaves hydrophobic slots created by the template cholesterol molecule. 16,17,23 Surface characterization imaged by AFM is given in Fig. S1 in Supporting Information.…”

“…[15][16][17] Cholesterol is essential for many metabolic processes, but high levels are often associated with heart disease. To know of its level in food as well as in our body, a number of papers related to electrochemical cholesterol sensors have been published based on enzymes, [18][19][20][21][22] molecularly imprinted polymers, 16,17,23,24 and other non-enzymatic approaches. 25,26 This article presents a SAM-based sensor optimized for food cholesterol.…”

Placement of Nanospace on an Electrode for Biosensing

“…Therefore, molecular imprinting can be described as a way of making an artificial "lock" for a molecular "key". [37][38][39][40][41] The construction of an MIP on an electrode combines the molecular imprinting method with electrical and electrochemical sensing techniques, resulting in effective measurement and signaling for a variety targets, [42][43][44][45][46] amino acids, [47][48][49][50] glucose, 51,52 cholesterol, [53][54][55][56][57] bile acids, 58 and others, [59][60][61][62][63] using an artificial component to mimic the biological receptor.…”