Molluscicidal activities of six species of Bignoniaceae from north–eastern Brazil, as measured against<i>Biomphalaria glabrata</i>under laboratory conditions

Silva, T. M. S.; Silva, T. G. da; Martins, Ronei Ximenes; Maia, Gabriela L. A.; Cabral, Analúcia Guedes Silveira; Câmara, Celso A.; Agra, María F.; Barbosa-Filho, José Maria

doi:10.1179/136485907x176427

Cited by 17 publications

(11 citation statements)

References 28 publications

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“…The final volume was 5 mL with mollusks exposed through dermal contact directly with the extract [ 12 ]. Silva and collaborators [ 13 ] used plastic terrariums with capacity of 250 mL containing 5 adult mollusks exposed to a final volume of 8 mL sprayed with manual sprayer.…”

Section: Discussionmentioning

confidence: 99%

“…There are papers using Becker with a maximal volume of 250 mL containing 10 mollusks for treatment [ 13 , 16 , 17 ], 500 mL with 10 mollusks [ 8 , 18 , 19 ], 1000 mL with 10 mollusks [ 20 , 21 ], and in rare cases 2000 mL [ 22 ]. However, these papers, changing the final volume and number of mollusks, did not validate mathematically the efficiency of these protocols to measure molluscicidal activity in comparison to standard protocol.…”

Section: Discussionmentioning

confidence: 99%

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A New Technique Using Low Volumes: A New Technique to Assess the Molluscicidal Activity Using Low Volumes

Santos

Cavalcante

Rangel

et al. 2017

Evidence-Based Complementary and Alternative Medicine

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Schistosomiasis is a disease endemic in several states of Brazil. The population control of the transmitter mollusks is done with Bayluscide WP 70®, in the control programs. OMS preconize molluscicidal assays using Becker with 500 mL of final volume, restringing the number of natural products and synthetic drugs to be tested in function of high quantity of material necessary. A new technique to assess the toxic effects for Biomphalaria sp. is the purpose of this work, for developing adaptation for this aquatic organism, using a low volume of test solution in 24-well plates. We used Biomphalaria glabrata (10–12 mm size) in a static system, consisting of the following components: Becker containing 10 snails or 24-well plates where snails were individualized for a volume of 2 mL per well for 24 and 48 hours. For the assays, we added aqueous solutions of Bayluscide WP 70, at a concentration of 1–5 mg/L, distilled water, and 1% dimethyl sulfoxide. Data were evaluated using Kappa's coefficient, Z factor validation, and comparison study. This technique to assess the toxic effect has proven to be a useful tool to detect lethal and sublethal effects, which could be used as a new evaluation protocol.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

A New Technique Using Low Volumes: A New Technique to Assess the Molluscicidal Activity Using Low Volumes

Santos

Cavalcante

Rangel

et al. 2017

Evidence-Based Complementary and Alternative Medicine

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“…Those chemical constituents provide its extracts with tensoactive properties, having been widely used not only as a source of soap but also for the application of its biological effects in medicine as well as in pest control. Indeed, the tensoactivity has been a property that has found application in pest control as shown by the fact that soaps are probably among the oldest insecticides in use (Silva et al 2007). …”

Section: Resultsmentioning

confidence: 99%

Bioactive Natural Products from Sapindaceae Deterrent and Toxic Metabolites Against Insects

Díaz¹,

Rossini²

2012

Insecticides - Pest Engineering

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“…O extrato etanólico de suas hastes evidenciou atividade moluscicida contra Biomphalaria glabrata com concentrações letais médias (9-54 µg ml -1 ) bem abaixo do limite superior de 100 µg ml -1 , estabelecido pela Organização Mundial de Saúde (Silva et al, 2007).…”

Section: Introductionunclassified

Avaliação do potencial biológico da Tabebuia aurea(Silva Manso) como fonte de moléculas bioativas para atividade antimicrobiana, antiedematogênica e antirradicalar

Santos

Conserva

Bastos

et al. 2015

Rev. bras. plantas med.

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RESUMO:As espécies da família Bignoniaceae e do gênero Tabebuia são amplamente utilizadas na medicina tradicional e possuem um forte potencial terapêutico. Diante disso, objetivou-se avaliar o potencial biológico da Tabebuia aurea, determinando a atividade antimicrobiana; por meio do método da microdiluição em caldo, para a determinação da Concentração Inibitória Mínima (CIM); antiedematogênica, pelo ensaio de edema de orelha induzido por capsaicina; e antirradicalar, frente ao radical DPPH. Os extratos etanólicos de T. aurea não evidenciaram citotoxicidade, exceto o extrato etanólico da flor nas concentrações > 0,5 mg mL -1 . O extrato etanólico da flor foi ativo com ação bactericida frente a S. epidermidis (CIM de 0,06 mg mL -1 ) enquanto o extrato etanólico da folha foi moderadamente ativo frente a S. epidermidis (CIM: 0,25 mg mL -1 ) e S. aureus (CIM: 0,50 mg mL -1 ) sugerindo ação bacteriostática para ambas as linhagens. Os dois extratos apresentaram ação antiedematogênica, com inibição do edema de 40,50% pelo extrato etanólico da flor e de 41,73% pelo extrato da folha. T. aurea não apresentou atividade antirradicalar. Os resultados comprovam o perfil antibacteriano e antiedematogênico com ausência de citotoxidade pela T. aurea. Sugere-se a continuação dos testes com frações e substâncias isoladas das flores e folhas da referida espécie vegetal, bem como de experimentos in vivo, como forma de agregar evidências visando à busca de novos fitoterápicos.Palavras-chave: Tabebuia aurea. Antimicrobianos. Viabilidade Celular.ABSTRACT: Biological potential assessment of Tabebuia aurea (Silva Manso) as a source of bioactive molecules for antimicrobial, antiedematogenic and antiradical activity. The species of Bignoniaceae family and genus Tabebuia are widely used in the traditional medicine and have a great therapeutic potential. The aim of the current research was to evaluate the biological potential of the Tabebuia aurea, determining its antimicrobial activity by the microdilution broth method, to predict the anti-edematogenic Minimum Inhibitory Concentration (MIC) by ear edema assay induced by capsaicin; and the antiradical one, towards DPPH. The ethanol extracts of T. aurea showed no cytotoxicity, except for the flower ethanol extract in concentrations above > 0.5 mg mL -1 . The ethanol extract of the flower was active, with bactericidal action, against S. epidermidis (MIC 0.06 mg ml -1 ) and the ethanol extract of moderately active recto S. epidermidis (CIM: 0.25 mg mL -1 ) and S. aureus (MIC: 0.50 mg mL -1 ) were bacteriostatic for both strains. Both extracts had antiedematogenic action on the inhibition of edema of 40.50% by the ethanol extract of the flower and 41.73% by leaf extract. T. aurea did not show antiradical activity. The results indicate the antibacterial and antiedematogenic profile with no cytotoxicity by the T. aurea. It suggests the continuation of tests with isolated fractions and substances of flowers and leaves of that plant species as well as in vivo trials, in order to enhance the evidence...

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Molluscicidal activities of six species of Bignoniaceae from north–eastern Brazil, as measured againstBiomphalaria glabrataunder laboratory conditions

Cited by 17 publications

References 28 publications

A New Technique Using Low Volumes: A New Technique to Assess the Molluscicidal Activity Using Low Volumes

A New Technique Using Low Volumes: A New Technique to Assess the Molluscicidal Activity Using Low Volumes

Bioactive Natural Products from Sapindaceae Deterrent and Toxic Metabolites Against Insects

Avaliação do potencial biológico da Tabebuia aurea(Silva Manso) como fonte de moléculas bioativas para atividade antimicrobiana, antiedematogênica e antirradicalar

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